Publications by Year (2018)

Atypical mycobacterial infections following plastic surgery procedures abroad: a multidisciplinary algorithm for diagnosis and treatment

Post Date: 
2018-12-28
Abstract: Medical tourism has become increasingly popular in recent years. The most commonly sought procedures are cosmetic. The recent rise in medical tourism has been mirrored by an increase in the incidence of M. abscessus infections, atypical mycobacteria ubiquitous in aquatic environments...

Building capacity for advances in tuberculosis research: Proceedings of the third RePORT International Meeting. Tuberculosis (Edinb)

Post Date: 
2018-12-15
Publication: 
Tuberculosis (Edinb)
Abstract RePORT International is a global network of research sites in India, Brazil, Indonesia, South Africa, China, and the Philippines dedicated to collaborative tuberculosis research in the context of HIV. A standardized research protocol (the Common Protocol) guides the enrollment...

Multiplex-PCR to detect pAmpC β-lactamases among Enterobacteriaceae at a tertiary care laboratory in Mumbai, India

Post Date: 
2018-12-13
   |   
Countries: 
India
   |   
Clinical Sites: 
Hinduja Hospital
Publication: 
Microbiology
Drug-resistance due to AmpC β-lactamases represents a growing problem worldwide. In this study, a previously collected sample of 108 cefoxitin-resistant clinical isolates was assessed for AmpC β-lactamase production through routine phenotypic testing and double-disc cefoxitin/cloxcallin (DD-CC),...

The mortality burden of multidrug-resistant pathogens in India: a retrospective observational study

Post Date: 
2018-11-08
   |   
Countries: 
India
Publication: 
Clinical Infectious Diseases
We conducted a retrospective, ten hospital study of the relationship between multidrug-resistant pathogens and mortality in India. This is one of the largest studies undertaken in an LMIC to measure the burden of antibiotic resistance.

The global landscape of tuberculosis therapeutics

Post Date: 
2018-11-07
Publication: 
Annual Review of Medicine
Abstract Tuberculosis (TB) is one of the oldest infections afflicting humans yet remains the number one infectious disease killer worldwide. Despite decades of experience treating this disease, TB regimens require months of multidrug therapy, even for latent infections...

Dengue vaccines: implications for dengue control

Post Date: 
2018-10-15
Publication: 
Current Opinion in Infectious Diseases
PURPOSE OF REVIEW: Dengue, the most common arbovirus, is an increasingly significant cause of morbidity worldwide. After decades of research, an approved tetravalent dengue vaccine is finally available. Models constructed using recently available vaccine efficacy data allow for a data-...

Drug-resistant Enterobacteriaceae colonization is associated with healthcare utilization and antimicrobial use among inpatients in Pune, India

Post Date: 
2018-10-04
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
BMC Infectious Diseases
BACKGROUND: Healthcare exposure may increase drug-resistant Enterobacteriaceae colonization risk. Nascent antimicrobial stewardship efforts in low- and middle-income countries require setting-specific data. We aimed to evaluate risk factors for inpatient drug resistant...

Barriers to screening and isoniazid preventive therapy for child contacts of tuberculosis patients

Post Date: 
2018-10-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
International Journal of Tuberculosis and Lung Disease
Universal, timely TB screening and IPT for exposed children are urgently needed to reduce pediatric TB in India

Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study

Post Date: 
2018-09-24
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
BMC Medicine
Factors identified through exploratory factor analysis were associated with adverse outcomes in HIV-infected individuals.

Report of the Technical Consultation on Advances in Clinical Trial Design for Development of New TB Treatments

Post Date: 
2018-09-17
Publication: 
WHO Task Force on Introduction of New TB Drugs and Treatment Regimens
Dr. Amita Gupta was a member of this TB technical consultation, convened in March 2018 in Switzerland.

Ovarian mass - tuberculosis or malignancy? Need for early intensified evaluation

Post Date: 
2018-09-14
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
EXCLI Journal
Letter to the Editor Dear Editor, We read with interest the case report by Chien et al. on Peritoneal Tuberculosis (TB) mimicking ovarian cancer (Chien et al., 2016[1]). We want to congratulate the authors on this case report. We encountered a similar case in our clinical setting in western India...

The association of household fine particulate matter and kerosene with tuberculosis in women and children in Pune, India

Post Date: 
2018-09-07
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Occupational and Environmental Medicine
Use of kerosene cooking fuel is positively associated with TB in women and children in our analysis using reported sources of exposure.

Challenges and opportunities for outreach workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) program in India

Post Date: 
2018-09-04
   |   
Countries: 
India
Publication: 
PLoS One
PLoS One: Prevention of Mother-to-Child Transmission of HIV program in India is one of the largest in the world, and it relies on outreach workers. Our study looked at challenges and opportunities for outreach workers.

Failure in TB control: why should the rapid diagnostic test bear the blame?

Post Date: 
2018-09-01
Publication: 
International Journal of Tuberculosis and Lung Disease
Dr. Sachit Atre's correspondence published in the International Journal of Tuberculosis and Lung Disease.

Resource utilization for multidrug-resistant tuberculosis household contact investigations (A5300/I2003)

Post Date: 
2018-09-01
   |   
Clinical Sites: 
BJGMC
Publication: 
International Journal of Tuberculosis and Lung Disease
Current guidelines recommend evaluation of the household contacts of individuals with multidrug-resistant tuberculosis; however, implementation of this policy is challenging.

The effect of diabetes mellitus on the pharmacokinetics and pharmacodynamics of tuberculosis treatment

Post Date: 
2018-08-20
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
DY Patil
NIRT
Publication: 
Antimicrobial Agents and Chemotherapy
DM and higher HbA1c increased the risk of not achieving therapeutic targets for pyrazinamide, but higher pyrazinamide concentrations were asociated with worse microbiologic and clinical outcomes

Challenges of TB and co-treatment: updates and insights

Post Date: 
2018-08-04
Publication: 
Current Opinion in HIV and AIDS
PURPOSE OF REVIEW: In the past few years, tuberculosis (TB) has overtaken HIV as the infectious disease with the highest global mortality. Successful management of this syndemic will require improved diagnostic tests, shorter preventive therapies, and more effective treatments,...

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting

Post Date: 
2018-08-01
   |   
Countries: 
India
Publication: 
PLoS One
World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

Post Date: 
2018-07-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
DY Patil
Publication: 
International Journal of Tuberculosis and Lung Disease
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months,...

Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

Post Date: 
2018-06-25
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
HIV Medicine
Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

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