Zika Surveillance among Antenatal Clinic Outpatients in BJ Government Medical College and Sassoon General Hospitals, Pune, India

Post Date: 
Clinical Sites: 

This study was terminated July 21, 2020.

Zika virus is a vector-borne disease carried by the mosquito Aedes aegypti. Pregnant women infected with Zika may pass the virus to the fetus, which may cause microcephaly and other severe brain defects. It is also linked to miscarriage, stillbirth, and other birth defects. Men infected with Zika can infect their sexual partners. There have also been increased reports of Guillain-Barré syndrome, an uncommon neurologic disorder, in areas affected by Zika. There is no vaccine or treatment for Zika.

As the implications of Zika infection during pregnancy could be devastating to the populations we serve, we will initiate screening in the antenatal clinic. Depending on the prevalence there, we will consider extending surveillance to other sections that may see patients with Zika, including other sections such as dermatology, general medicine, paediatrics, etc.


  1. To determine the prevalence of Zika-like signs and symptoms among pregnant women attending ANC outpatient department (OPD) at Sassoon Hospital, Pune.

  2. To determine the prevalence of Zika-like signs and symptoms among the general population attending OPDs other than ANC at Sassoon Hospital, Pune.

  3. To follow up these patients for resolution and sequelae of the infection.

  4. To determine the prevalence of acute Zika infection among pregnant women attending ANC OPD who have Zika-like signs or symptoms.