Maternal tuberculosis: a risk factor for mother-to-child transmission of human immunodeficiency virus

Post Date: 
2011-02-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
The Journal of Infectious Diseases
Background: Maternal human immunodeficiency virus (HIV) RNA load, CD4 cell count, breast-feeding, antiretroviral use, and malaria are well-established factors associated with mother-to-child transmission (MTCT) of HIV; the role of maternal tuberculosis (TB), however, has not been well...

Public private partnerships for emergency obstetric care: lessons from Maharashtra

Post Date: 
2011-01-15
   |   
Countries: 
India
Publication: 
Indian Journal of Community Medicine
Abstract Background: The National Rural Health Mission of India advocates public private partnerships (PPPs) to meet its "service guarantee" of Emergency obstetric care (EmOC) provision. The Janani Suraksha Yojana (JSY) has a provision of Rs. 1500 for contracting in...

Tuberculosis in women and children

Post Date: 
2010-12-15
Publication: 
The Lancet
Apart from improvement of tuberculosis control, innovative strategies to advance tuberculosis prevention and treatment in women and children would contribute to the attainment of Millennium Development Goals 4 and 5 by reduction of the mortality rate in young children and women of...

Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: an analysis of three randomized controlled trials

Post Date: 
2009-07-26
   |   
Countries: 
Ethiopia
India
Uganda
   |   
Clinical Sites: 
BJGMC
Publication: 
The Lancet
Background: UNICEF/WHO recommends that infants born to HIV-infected mothers who do not have access to acceptable, feasible, affordable, sustainable, and safe replacement feeding should be exclusively breastfed for at least 6 months. The aim of three trials in Ethiopia, India, and Uganda was...

Nevirapine resistance and breast-milk HIV transmission: effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants

Post Date: 
2009-01-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
PLOS One
Background: Daily nevirapine (NVP) prophylaxis to HIV-exposed infants significantly reduces breast-milk HIV transmission. We assessed NVP-resistance in Indian infants enrolled in the “six-week extended-dose nevirapine” (SWEN) trial who received single-dose NVP (SD-NVP) or SWEN for prevention...

Modeling maternal infant HIV transmission in the presence of breast-feeding with an imperfect test

Post Date: 
2007-12-15
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Biometrics
An important public health question is to determine the probabilities of perinatal HIV transmission and when it occurs, whether antepartum, intrapartum, or postpartum through breastfeeding. However, this is a difficult problem because the presence of HIV infection in an infant can only be...

Are we really making motherhood safe? A study of provision of iron supplements and emergency obstetric care in rural Maharashtra

Post Date: 
2007-11-30
   |   
Countries: 
India
Publication: 
National Medical Journal of India
Abstract Background: The Government of India launched the National Rural Health Mission (NRHM) in 2005 to improve healthcare delivery and strengthen the public health system. Prevention and management of anaemia during pregnancy and access to quality emergency obstetric care...

Mother-to-child transmission of HIV among women who chose not to exclusively breastfeed their infants in Pune, India

Post Date: 
2007-08-15
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Indian Journal of Medical Research
Background and Objective: The percentage of HIV cases attributed to mother-to-child transmission (MTCT) has increased several fold in recent years. No reports are available on HIV MTCT rates among HIV-infected choosing not be exclusively breastfeed their infants in India. We examined HIV MTCT...

Post-partum TB incidence and mortality among HIV-infected women and their infants in Pune, India 2002-2005

Post Date: 
2007-07-15
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Clinical Infectious Diseases
Background: In contrast with many other countries, isoniazid preventative therapy is not recommended in clinical care guidelines for human immunodeficiency virus (HIV)-infected persons with latent tuberculosis (TB) in India. Methods: Seven hundred fifteen...

Clinically significant anemia in HIV-infected pregnant women in India is not a major barrier to zidovudine use for prevention of maternal-to-child transmission

Post Date: 
2007-06-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Objectives: To determine the prevalence of anemia (serum hemoglobin <10 g/dL) and assess zidovudine use and toxicity in HIV-positive pregnant women in India. Methods: From 2002 through 2006, 24,105 pregnant women in Pune were screened for HIV and anemia. As part of...

Impact of maternal HIV co-infection on the vertical transmission of Hepatitis C virus: a meta-analysis.

Post Date: 
2007-04-15
Publication: 
Clinical Infectious Diseases
Background: Observational studies suggest that maternal human immunodeficiency virus (HIV)-hepatitis C virus (HCV) coinfection is associated with increased odds of vertical HCV transmission. We performed a meta-analysis to summarize current evidence. Methods...

Feasibility of voluntary counseling and testing services for HIV among pregnant women presenting in labor in Pune, India

Post Date: 
2005-08-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
international Journal of STD &amp; AIDS
Factors affecting the eligibility and acceptability of voluntary counselling and rapid HIV testing (VCT) were examined among pregnant womenpresenting in labour in Pune, India. Of the 6702 total women appearing at the delivery room from April 2001 to March 2002, 4638 (69%) were admitted for...

Making the choice: the translation of global HIV and infant feeding policy to local practice among mothers in Pune, India

Post Date: 
2005-04-15
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
The Journal of Nutrition
In 2003, India had over 5.1 million infected individuals living with HIV/AIDS. The percentage of all HIV cases attributed to perinatal transmission has been increasing steadily from 0.33% of total cases in 1999 to 2.80% in 2004. Recent statistics indicate that over 130,000 infants have been...

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