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Mental Health Outcomes among Health Care Professionals Involved in the Treatment and Care of COVID 19 Patients in India

Post Date:

2020-06-01

Countries:

Clinical Sites:

Drs. Nikhil Gupta and Nishi Suryavanshi are leading this survey project. This study is investigating the immediate impact of the COVID-19 pandemic on mental health outcomes and overall quality of life and what are the factors associated with it among Indian Health care workers. Among health care...

Visual Field Loss in HIV-Positive Patients of Non-Infectious HIV Retinopathy

Post Date:

2019-06-02

Countries:

India

Clinical Sites:

BJGMC

New study will assess HIV+ patients and determine the prevalence of visual field loss due to noninfectious HIV retinopathy

Implementing the Comprehensive Unit-based Safety Program to Reduce Healthcare-Associated Sepsis in the Neonatal Intensive Care Unit in Pune, India

Post Date:

2018-04-19

Countries:

India

Clinical Sites:

BJGMC

DY Patil

This study is part of CDC's Safe Healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Program under Domain 7: International HAI and Other Adverse Healthcare Event Prevention. Dr. Aaron Milstone is the PI, and Dr. Amita Gupta and Yuka Manabe are Co-PIs. The Study...

The Role of GeneXpert in Bacterial Diagnosis of Spinal Tuberculosis

Post Date:

2017-10-26

Countries:

India

Clinical Sites:

BJGMC

This study was teriminated June 19, 2019. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. India has the maximum burden of tuberculosis (TB) in the world. In 2014, there were an estimated 9.6 million incident...

Zika Surveillance among Antenatal Clinic Outpatients in BJ Government Medical College and Sassoon General Hospitals, Pune, India

Post Date:

2017-08-31

Countries:

India

Clinical Sites:

BJGMC

This study was terminated July 21, 2020. Zika virus is a vector-borne disease carried by the mosquito Aedes aegypti . Pregnant women infected with Zika may pass the virus to the fetus, which may cause microcephaly and other severe brain defects. It is also linked to...

Optimizing Treatment to Improve TBM Outcomes in Children: Substudy on Clinical Profile and CSF Biorepository of the Pediatric Suspected Meningitis Cases

Post Date:

2017-07-18

Countries:

Clinical Sites:

This sub-study is being led by PIs Dr. Kelly Dooley and Dr. Chhaya Valvi. Meningoencephalitis is associated with significant morbidity and mortality. Several viruses, bacteria, and fungal pathogens including Neisseria meningitidis, Streptococcus pneumoniae, Mycobacterium...

A5332: Randomized Trial to Prevent Vascular Events in HIV – REPRIEVE

Post Date:

2017-06-09

Countries:

India

Clinical Sites:

BJGMC

This study is conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. This is a prospective, double-blind, randomized, placebo-controlled, multicenter efficacy study in 6500 subjects, with individual subjects to be followed...

Bacterial Antimicrobial Resistance Patterns in Pune, India: Substudy on the Introduction of Triage to a Triage Naïve Emergency Department in Pune, India, and the Effects on Patient Flow

Post Date:

2017-01-01

Countries:

India

Clinical Sites:

BJGMC

Despite state-of-the-art inpatient facilities, Sassoon General Hospital (SGH) in Pune, India, does not currently have a method of triaging the large volume of patients they care for on a daily basis. Based on prior studies in low to middle income countries...

Optimal Algorithmic Diagnosis of Genital TB among HIV-infected and Uninfected Infertile Women

Post Date:

2016-05-26

Countries:

India

Clinical Sites:

BJGMC

This study was terminated March 2020. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. There is a lack of a set protocol universally for diagnosis of genital TB, and for Indian hospitals, India's Revised National...

Smallpox Comes Back to Life in Microbe Hunters

Post Date:

2015-10-22

Baltimore, MD—The world may have been declared free of smallpox in 1980, but the eradication campaign was revived Tuesday in a multimedia presentation at the Johns Hopkins Medical Campus. The event featured a screening of the film Microbe Hunters: Smallpox , by the Johns...

Prevalence Survey of Risk Factors for Tuberculosis and Non-communicable Diseases in an HIV-positive Population in Pune, India

Post Date:

2015-08-17

Countries:

India

Clinical Sites:

BJGMC

This study is conducted under the TREAT Asia Network and funded by amfAR. The primary objective of this study is to assess the prevalence of risk factors for tuberculosis and non-communicable diseases (NCDs)--coronary artery disease and diabetes mellitus--...

A Prospective Study Evaluating the Role of Cryptococcal Antigen Screening among HIV-infected Adults with Low CD4 Counts

Post Date:

2011-01-01

Countries:

India

Clinical Sites:

BJGMC

This prospective observational study aimed to evaluate the burden of cryptococcal disease among approximately 200 HIV-infected adults with low CD4 cell counts in Pune, India to determine whether a Cryptococcal screening strategy should be the standard of care among patients with advanced HIV...

Hospitalized Pediatric Patients with Pandemic 2009 H1N1 Influenza in India (August-November 2009)

Post Date:

2010-04-10

Countries:

India

Clinical Sites:

BJGMC

This study ended in April 2013. This was a review and collection of data from the medical records of pediatric patients who were admitted to the BJMC/Sassoon General Hospitals with H1N1 influenza during August-November 2009.

Evaluation of the Impact of Distance Learning For Expanding Capacity for Clinical Research in India

Post Date:

2009-02-13

Countries:

India

This study ended in March 2012. The Office of AIDS Research has initiated a comprehensive program to expand clinical research capacity in India. This program has utilized a number of platforms for providing research training, including intensive in-country workshops and conferences. These programs...

Cryptococcal Meningitis among Hospitalized HIV Patients in India (June 2008–June 2010)

Post Date:

2008-06-30

Countries:

India

Clinical Sites:

BJGMC

This study was terminated in 2016. Cryptococcal meningitis secondary to HIV infection is one of the leading causes of mortality from infectious agents worldwide. Recent estimates suggest close to a million infections annually and over six hundred thousand deaths every year. South and Southeast Asia...

Aspergillosis Complicating Severe Coronavirus Disease

Post Date:

2021-01-01

Countries:

Spain

United States

Publication:

EID Journal

Aspergillosis complicating severe influenza infection has been increasingly detected worldwide. Recently, coronavirus disease–associated pulmonary aspergillosis (CAPA) has been detected through rapid reports, primarily from centers in Europe. We provide a case series of CAPA, adding 20 cases to the...

Chronic Obstructive Pulmonary Disease Endotypes in Low- and Middle-Income Country Settings: Precision Medicine for All

Post Date:

2020-07-15

Publication:

Am J Respir Crit Care Med

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease marked by largely irreversible airflow obstruction due to small airway obstruction and emphysema that results from complex gene–environment interactions over the lifespan of an individual. Although the clinical definition of...

High Burden of Bloodstream Infections Associated with Antimicrobial Resistance and Mortality in the Neonatal Intensive Care Unit in Pune, India

Post Date:

2020-05-18

Publication:

Clinical Infectious Diseases

Background: Antimicrobial resistance (AMR) is a growing threat to newborns in low and middle income countries (LMIC). Methods: We performed a prospective cohort study in three tertiary Neonatal Intensive Care Units (NICUs) in Pune, India, to describe the epidemiology of neonatal bloodstream...

Evaluating the Concordance of Clinician Antiretroviral Prescribing Practices and HIV-ASSIST, an Online Clinical Decision Support Tool

Post Date:

2019-12-02

Countries:

India

Publication:

Journal of General Internal Medicine

Recent studies have shown that more than half of HIV care is provided by primary care practitioners.However, clinicians with experience and expertise in HIV medicine are declining.

Challenges in conducting trials for pediatric tuberculosis meningitis: lessons learned in the field

Post Date:

2019-10-01

Countries:

India

Clinical Sites:

BJGMC

NIRT

Publication:

International Journal of Tuberculosis and Lung Disease

International Journal of Tuberculosis and Lung Disease: Researchers describe the challenges associated with conducting the first randomized clinical trial of antimicrobial agents in pediatric tuberculosis meningitis.

Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study

Post Date:

2019-07-29

Countries:

India

Clinical Sites:

BJGMC

Publication:

Lancet HIV

BACKGROUND: Antiretroviral therapy (ART) management is challenging for individuals in resource-limited settings presenting for third-line treatment because of complex resistance patterns, partly due to reduced access to viral load monitoring. We aimed to evaluate use of newer...

Users beware! Biological variation in complete blood counts over short time intervals

Post Date:

2019-05-29

Publication:

BMJ Evidence Based Medicine

New publication in BMJ Evidence Based Medicine looks at CBC count variations in blood drawn over a short time period

Female global health leadership: Data-driven approaches to close the gender gap

Post Date:

2019-02-09

Countries:

India

Clinical Sites:

BJGMC

Publication:

The Lancet

Lancet article investigates gender-based challenges of female health trainees and professionals and identifies interventions

Atypical mycobacterial infections following plastic surgery procedures abroad: a multidisciplinary algorithm for diagnosis and treatment

Post Date:

2018-12-28

Abstract: Medical tourism has become increasingly popular in recent years. The most commonly sought procedures are cosmetic. The recent rise in medical tourism has been mirrored by an increase in the incidence of M. abscessus infections, atypical mycobacteria ubiquitous in aquatic environments...

Dengue vaccines: implications for dengue control

Post Date:

2018-10-15

Publication:

Current Opinion in Infectious Diseases

PURPOSE OF REVIEW: Dengue, the most common arbovirus, is an increasingly significant cause of morbidity worldwide. After decades of research, an approved tetravalent dengue vaccine is finally available. Models constructed using recently available vaccine efficacy data allow for a data-...

The global neurological burden of tuberculosis

Post Date:

2018-05-18

Publication:

Seminars in Neurology

Central nervous system (CNS) involvement of tuberculosis (TB) is the most severe manifestation of TB and accounts for approximately 5 to 10% of all extrapulmonary TB (EPTB) cases and approximately 1% of all TB cases. TB meningitis (TBM) is the most common form of CNS TB, though other forms...

Re: How serious are global health leaders about gender equality?

Post Date:

2018-04-06

Publication:

British Medical Journal

Letter to the Editor: At the 2017 Consortium of Universities for Global Health (CUGH) in Washington, D.C., a panel of female global health leaders (AG, MB, IK, JM, YM) discussed the barriers to female leadership and put forward actionable advice on how to address them.

Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016

Post Date:

2017-09-16

Publication:

The Lancet

Abstract Background: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to...

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Post Date:

2017-09-16

Publication:

The Lancet

Abstract Background: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD...

Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016

Post Date:

2017-09-12

Publication:

The Lancet

Abstract Background: The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of "leaving no one behind". Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As...

Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015

Post Date:

2017-07-15

Publication:

The Lancet

Abstract Background: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to...

Cardiovascular risk in an HIV-infected population in India

Post Date:

2017-07-03

Countries:

India

Clinical Sites:

BJGMC

Publication:

Heart Asia

Findings: HIV+ Indian patients who had cardiovascular disease at a younger age appear to be at imminent risk for morbidity.

A qualitative study exploring factors influencing clinical decision-making for influenza-like illness in Solapur city, Maharashtra, India

Post Date:

2017-07-03

Countries:

India

Publication:

Anthropology and Medicine

Abstract The co-existence of different types of medical systems (medical pluralism) is a typical feature of India's healthcare system. For conditions such as influenza-like illness (ILI), where non-specific disease signs/symptoms exist, clinical reasoning in the context of medical...

Presence of human hepegivirus-1 in a cohort of people who inject drugs

Post Date:

2017-06-07

Publication:

Annals of Internal Medicine

Findings on the sensitivity of next-generation metagenomic sequencing for discovery of new viral infections.

The ripple effect: why promoting female leadership in global health matters

Post Date:

2016-12-21

Publication:

Public Health Action

Leadership positions in global health are greatly skewed toward men; the imbalance is more pronounced in low- and middle-income countries (LMICs). The under-representation of women in leadership is a threat to gender equality, and also impacts the improvement of women's health outcomes...

FE Cardiology Summit, Cardiovascular Diabetes – A Growing Concern.

Post Date:

2021-10-05

Amita Gupta joined the FE Cardiology Summit to discuss the intersection of cardiovascular disease, diabetes, and COVID-19. Check out what she has to say

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