All Studies/Projects

All Projects
By Topic
By Staff

Optimizing Treatment to Improve TBM Outcomes in Children

Post Date:

2014-05-01

Countries:

India

Clinical Sites:

BJGMC

NIRT

This study, known as TBM Kids, is being conducted in India and Malawi. Primary Objectives To characterize the pharmacokinetics (PK) (plasma and cerebrospinal fluid (CSF)) of rifampicin given at model-derived optimal daily doses and...

P1078: A Phase IV Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety of Immediate (Antepartum-Initiated) Versus Deferred (Postpartum-Initiated) Isoniazid Preventive Therapy Among HIV-Infected Women in High TB Incidence Settings

Post Date:

2014-04-01

Countries:

India

Clinical Sites:

BJGMC

This is a clinical trial conducted under the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network and funded by the U.S. National Institutes of Health. Dr. Amita Gupta is Protocol Chair for this multinational clinical trial being conducted in...

Screening for Gender Based-violence (GBV) and Feasibility and Acceptability of mHealth GBV Screening and Support Tools

Post Date:

2014-03-26

Countries:

India

Clinical Sites:

BJGMC

This study was terminated February 14, 2017. Gender-based violence (GBV) is a significant public health issue in India, with estimates that over a third of women and girls are impacted at some point in their lifetime. This pilot qualitative study examined the feasibility of enhancing GBV prevention...

Evaluation of HIV Disease Burden in Hospitalized Patients at Sassoon General Hospital in Pune, India

Post Date:

2013-11-18

Countries:

India

Clinical Sites:

BJGMC

This study was terminated September 13, 2005. The goal of this project was to conduct both a retrospective and prospective epidemiological study of the burden of HIV disease at Sassoon General Hospital. The specific objectives of the study were to establish the proportion of...

Tuberculosis Noon Conference

Post Date:

2013-10-24

Countries:

Clinical Sites:

This effort ended in 2015. As part of the BJGMC-Johns Hopkins India Fogarty Training Program, from 2013-2015 CCGHE hosted the live Tuberculosis Noon Conference webcast. Led by Drs. Maunank Shah, Jonathan Golub, and Richard Chaisson, these webcast meetings brought together Johns Hopkins TB...

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH)

Post Date:

2013-09-28

Countries:

India

Clinical Sites:

BJGMC

NIRT

Collaboratively funded by the US NIH, India’s Department of Biotechnology [DBT], and Indian Council of Medical Research, the Cohort for TB Research by the Indo-US Medical Partnership (C-TRIUMPH) is an Indo-US research consortium that is part of RePORT India, a countrywide consortium for TB...

Ecobiosocial Approach for Dengue Vector Control

Post Date:

2013-09-15

Countries:

Colombia

Dengue is a major public health concern in the Region of the Americas. Working in a dengue endemic area of Colombia, the Centro de Estudios e Investigación en Salud (CEIS) Fundación Santa Fe de Bogotá conducted a multisite study focused on improved dengue prevention. CCGHE and Fundacion Santa Fe d...

Assessing the Association of Indoor Air Pollution with Tuberculosis in Adult Women and Children under 5 Years of Age

Post Date:

2013-09-15

Countries:

India

This study is conducted the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Addressing social and...

Perceptions and Acceptability of mHealth Interventions: A Mixed Methods Study Using emocha®

Post Date:

2013-09-14

Countries:

Uganda

This comprehensive formative research study was designed to help guide the development and implementation of novel, task-shifting mHealth HIV/AIDS care interventions at a community-based HIV/AIDS clinic in Kampala, Uganda. Using emocha®, important knowledge was gained on acceptability and...

Community Home Based India Prevention of Mother to Child Transmission of HIV (COMBIND)

Post Date:

2013-09-02

Countries:

India

Clinical Sites:

BJGMC

This study ended May 14, 2019. CCGHE is assessing whether equipping Community Health Workers with mobile health technology and involving them in technology training and personal empowerment seminars can help prevent mother-to-child...

Epidemiological Assessment of Pediatric Tuberculosis in Pune, India, through Contact Tracing

Post Date:

2013-06-10

Countries:

India

This study ended in June 2016. Approximately 1 million new cases of Tuberculosis occur among children each year around the world, with a large number of these cases occurring among indigent populations without access to adequate healthcare facilities (World Health Organization). Due to their high...

Hair Concentrations of Anti-tuberculosis Drugs Among HIV-infected and Uninfected Children in India

Post Date:

2013-05-07

Countries:

India

Clinical Sites:

BJGMC

NIRT

This study was terminated May 15, 2017. In the developing world, tuberculosis (TB) is a major cause of mortality among HIV-infected children, a population where measuring treatment adherence and drug levels is difficult. We propose an innovative therapeutic...

TB Case Conference

Post Date:

2013-02-25

Countries:

United States

CCGHE broadcasts live TB Case Conferences and provides a global audience with open access to all live and archived webcasts via the CCGHE website. Hosted by Dr. Maunank Shah (Johns Hopkins), this case-based conference serves as a forum where clinicians caring for individuals with active TB can...

Impact of Diabetes on TB Treatment Outcomes

Post Date:

2013-02-01

Countries:

India

Clinical Sites:

BJGMC

DY Patil

CCGHE, the JHU Center for TB Research and BJGMC have been awarded a $2.5 million dollar NIH grant (2013-2018) to conduct a study to evaluate treatment outcomes among Indian patients with both diabetes mellitus and active TB. This study is assessing the prevalence of impaired glucose or frank...

Bacterial Antimicrobial Resistance Patterns in Pune, India

Post Date:

2013-01-10

Countries:

India

Clinical Sites:

BJGMC

DY Patil

This study was terminated September 24, 2019. Evaluate etiology of acute fever and bacterial drug resistance patterns among adults and children in India.

ONCOGRID: An mHealth Approach to Prevention and Early Diagnosis of Oral Cancer in Rural South India

Post Date:

2012-11-01

Countries:

India

This study ended February 7, 2017. The Indian sub-continent is burdened with 80% of the world’s patients with oral cancer, and delay in oral cancer diagnosis is one of the major problems that leads to poor treatment outcomes (V. Shanta, R. Swaminathan, R...

Diagnosis of Active Tuberculosis in HIV-infected and Uninfected Young Children in India

Post Date:

2012-07-24

Countries:

India

Clinical Sites:

BJGMC

Tuberculosis (TB) is the most common cause of morbidity/mortality in HIV-infected individuals in India. India has the world's highest burden of HIV and TB, and since children acquire HIV/TB from their caregivers, active TB is highly prevalent (14-67.5%) among HIV-infected young children in...

ACTG 5279: Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals with Latent Tuberculosis Infection

Post Date:

2012-07-23

Countries:

India

Clinical Sites:

BJGMC

This study was terminated April 27, 2015. Dr. Amita Gupta is Protocol Co-Vice Chair for this multinational clinical trial being conducted in Botswana, Brazil, Haiti, Kenya, Malawi, Peru, Puerto Rico, South Africa, Tanzania, Thailand, Uganda, United States, Zambia, Zimbabwe, and India by the...

A5288: MULTIOCTAVE, Management Using the Latest Technologies in Resource-limited Settings to Optimize Combination Therapy After Viral Failure

Post Date:

2012-07-16

Countries:

India

This study was terminated in March 2020. It was a mult-country clinical trial conducted in Brazil, Haiti, India, Kenya, Malawi, Peru, South Africa, Thailand, Uganda, and Zambia under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. ...

RePORT India

Post Date:

2012-06-30

Countries:

Clinical Sites:

RePORT India is a joint venture between the Indian and US governments. The Indo-US Vaccine Action Program, a collaboration between the Indian Department of Biotechnology (DBT), the Indian Council of Medical Research (ICMR), and the US NIH, is co-funding six teams of India- and US-based...