Publications

All Publications
By Topic
By Staff

The effect of diabetes mellitus on the pharmacokinetics and pharmacodynamics of tuberculosis treatment

Post Date:

2018-08-20

Countries:

Clinical Sites:

Publication:

Antimicrobial Agents and Chemotherapy

DM and higher HbA1c increased the risk of not achieving therapeutic targets for pyrazinamide, but higher pyrazinamide concentrations were asociated with worse microbiologic and clinical outcomes

Challenges of TB and co-treatment: updates and insights

Post Date:

2018-08-04

Publication:

Current Opinion in HIV and AIDS

PURPOSE OF REVIEW: In the past few years, tuberculosis (TB) has overtaken HIV as the infectious disease with the highest global mortality. Successful management of this syndemic will require improved diagnostic tests, shorter preventive therapies, and more effective treatments,...

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting

Post Date:

2018-08-01

Countries:

India

Publication:

PLoS One

World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

Post Date:

2018-07-01

Countries:

India

Clinical Sites:

BJGMC

DY Patil

Publication:

International Journal of Tuberculosis and Lung Disease

SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months,...

Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

Post Date:

2018-06-25

Countries:

India

Clinical Sites:

BJGMC

Publication:

HIV Medicine

Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

Diabetes and prediabetes among household contacts of tuberculosis patients in India: Is it time to screen them all?

Post Date:

2018-06-01

Countries:

India

Clinical Sites:

BJGMC

Publication:

International Union Against Tuberculosis and Lung Disease

SETTING: Pre-diabetes mellitus (pre-DM) and DM increase the risk of developing tuberculosis (TB). Screening contacts of TB patients for pre-DM/DM and linking them to care may mitigate the risk of developing TB and improve DM management. OBJECTIVE: To measure the prevalence of pre-DM/DM and...

Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial

Post Date:

2018-05-29

Countries:

India

Publication:

Clinical Nutrition

Nutritional deficiency and inflammation may impact CD4+ T cell recovery during combination antiretroviral therapy (cART), particularly in resource-limited settings where malnutrition is prevalent. The aim of this study was to investigate the relationship of micronutrient and inflammation biomarkers to CD4 recovery after cART initiation.

Sources of household air pollution and their association with fine particulate matter in low-income urban homes in India

Post Date:

2018-05-23

Countries:

India

Clinical Sites:

BJGMC

Publication:

Journal of Exposure Science and Environmental Epidemiology

INTRODUCTION: Household air pollution (HAP) is poorly characterized in low-income urban Indian communities. MATERIALS AND METHODS: A questionnaire assessing sources of HAP and 24 h household concentrations of particulate matter less than 2.5 microns in diameter (...

Diabetes and pre-diabetes among household contacts of tuberculosis patients in India: is it time to screen them all?

Post Date:

2018-05-22

Countries:

India

Clinical Sites:

BJGMC

Publication:

The International Journal of Tuberculosis and Lung Disease

Authors find that screening contacts of TB patients for pre-DM/DM and linking them to care may mitigate the risk of developing tuberculosis and improve management of diabetes.

The global neurological burden of tuberculosis

Post Date:

2018-05-18

Publication:

Seminars in Neurology

Central nervous system (CNS) involvement of tuberculosis (TB) is the most severe manifestation of TB and accounts for approximately 5 to 10% of all extrapulmonary TB (EPTB) cases and approximately 1% of all TB cases. TB meningitis (TBM) is the most common form of CNS TB, though other forms...

Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India

Post Date:

2018-05-02

Countries:

India

Clinical Sites:

BJGMC

Publication:

Clinical Infectious Diseases

Mosquito-borne disease identification is associated with reduced empiric antibiotic use and faster antibiotic discontinuation.

Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination

Post Date:

2018-05-02

Countries:

India

Clinical Sites:

BJGMC

Publication:

BMC Infectious Diseases

BMC Infectious Diseases : Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

Hepatotoxicity during isoniazid preventive therapy and antiretroviral therapy in people living with HIV with severe immunosuppression: a secondary analysis of a multi-country open-label randomized controlled clinical trial

Post Date:

2018-05-01

Publication:

Journal of Acquired Immune Deficiency Syndromes

BACKGROUND: Hepatotoxicity associated with isoniazid preventive therapy (IPT) and antiretroviral therapy (ART) has not been well studied in severely immunosuppressed people with HIV. Our objective was to determine risk factors for hepatotoxicity in severely immunosuppressed individuals...

MDR-TB in children: back to the basics

Post Date:

2018-05-01

Countries:

India

Publication:

The International Journal of Tuberculosis and Lung Disease

IJTLD: Summary of the Pediatric Multidrug-Resistant Tuberculosis Clinical Trials Landscape Meeting: a primer of current directions.

Shorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial

Post Date:

2018-04-19

Countries:

India

Clinical Sites:

BJGMC

Publication:

Trials

Trials: Evidence for TB treatment in kids is largely based on adult studies. The SHINE study aims to fix this

Re: How serious are global health leaders about gender equality?

Post Date:

2018-04-06

Publication:

British Medical Journal

Letter to the Editor: At the 2017 Consortium of Universities for Global Health (CUGH) in Washington, D.C., a panel of female global health leaders (AG, MB, IK, JM, YM) discussed the barriers to female leadership and put forward actionable advice on how to address them.

Prevention of HIV-1 transmission through breastfeeding:efficacy of safety of maternal antiretroviral therapy versus infant nevirapine prophylaxis for duration of breastfeeding in HIV-1-infected women with high CD4 cell count (IMPAACT PROMISE)

Post Date:

2018-04-01

Countries:

India

Clinical Sites:

BJGMC

Publication:

Journal of Acquired Immune Deficiency Syndromes

BACKGROUND: No randomized trial has directly compared the efficacy of prolonged infant antiretroviral prophylaxis versus maternal antiretroviral therapy (mART) for prevention of mother-to-child transmission throughout the breastfeeding period. SETTING: Fourteen...

Screening and diagnosis of gestational diabetes in India: A systematic review and meta analysis

Post Date:

2018-03-26

Countries:

India

Publication:

Acta Diabetologica

Review article on prevalence and screening and diagnostic methods for gestational diabetes in India.

Vector-borne disease is a common cause of hospitalized febrile illness in India

Post Date:

2018-03-26

Clinical Sites:

BJGMC

Publication:

American Journal of Tropical Medicine and Hygiene

Diagnostic strategies adapted for season and age may reduce diagnostic uncertainty and identify causative organisms in treatable, fatal causes of AFI.