2023 Publications

Explore our research findings.


Early Microbiologic Markers of Pulmonary Tuberculosis Treatment Outcomes
Paradkar MS, Pradhan NN, Balaji S, Gaikwad SN, Chavan A, Dharmashale SN, Sahasrabudhe T, Lokhande R, Deshmukh SA, Barthwal M, Atre S, Raskar SS, Sawant TU, Gupte AN, Kakrani A, Golub J, Padmapriyadarsini C, Gupta A, Gupte NA, Mave V. Ann Am Thorac Soc. 2023 Dec 15;20(12):1760-1768. doi: 10.1513/AnnalsATS.202302-144OC. PMID: 38038600; PMCID: PMC10704230.

The sound of silent RNA in tuberculosis and the lncRNA role on infection
Rocha EF, Vinhaes CL, Araújo-Pereira M, Mota TF, Gupte AN, Kumar NP, Arriaga MB, Sterling TR, Babu S, Gaikwad S, Karyakarte R, Mave V, Kulkarni V, Paradkar M, Viswanathan V, Kornfeld H, Gupta A, Andrade BB, Queiroz ATL; RePORT Brazil; RePORT India Consortia. iScience. 2023 Dec 8;27(1):108662. doi: 10.1016/j.isci.2023.108662. PMID: 38205253; PMCID: PMC10777062.


Tuberculin test using Indian indigenous purified-protein derivative (PPD) shows only moderate agreement with international standard PPD
Christopher DJ, Priya N, Shankar D, Isaac B, DeLuca A, Sarkar S, Prakash Babu S, Samuel P, Cattamanchi A, Gupta A, Ellner J, Srinivasan S, Cox S, Thangakunam B. J Clin Tuberc Other Mycobact Dis. 2023 Dec 1;34:100404. doi: 10.1016/j.jctube.2023.100404. PMID: 38174327; PMCID: PMC10761766.

Cumulative violence exposures among men who have sex with men living with HIV in India: Psychosocial correlates of HIV care continuum outcomes
Sabri B, Budhathoki C, McFall AM, Mehta SH, Celentano DD, Solomon SS, Srikrishnan AK, Anand S, Vasudevan CK, Lucas GM. PLoS One. 2023 Dec 1;18(12):e0295225. doi: 10.1371/journal.pone.0295225. PMID: 38039322; PMCID: PMC10691715.

Timing of maternal isoniazid preventive therapy on tuberculosis infection among infants exposed to HIV in low-income and middle-income settings: a secondary analysis of the TB APPRISE trial
Gupta A, Singh P, Aaron L, Montepiedra G, Chipato T, Stranix-Chibanda L, Chanaiwa V, Vhembo T, Mutambanengwe M, Masheto G, Raesi M, Bradford S, Golner A, Costello D, Kulkarni V, Shayo A, Kabugho E, Jean-Phillippe P, Chakhtoura N, Sterling TR, Theron G, Weinberg A; IMPAACT P1078 TB APPRISE Study Team. Lancet Child Adolesc Health. 2023 Oct 15;7(10):708-717. doi: 10.1016/S2352-4642(23)00174-8. Epub 2023 Aug 24. PMID: 37634517; PMCID: PMC10883460.

Changes in HIV care continuum indicators among community-based samples of HIV-infected people who inject drugs and men who have sex with men across 21 cities in India
Prata Menezes NS, Solomon SS, McFall AM, Srikrishnan AK, Vasudevan CK, Kumar MS, Celentano DD, Mehta SH, Lucas GM. AIDS Care. 2023 Oct 15;35(10):1570-1579. doi: 10.1080/09540121.2022.2119470. Epub 2022 Sep 17. PMID: 36120904; PMCID: PMC10020120.

Hepatitis C
Martinello M, Solomon SS, Terrault NA, Dore GJ. Lancet. 2023 Sep 23;402(10407):1085-1096. doi: 10.1016/S0140-6736(23)01320-X. PMID: 37741678.

1-Year Incidence of Tuberculosis Infection and Disease Among Household Contacts of Rifampin- and Multidrug-Resistant Tuberculosis
Krishnan S, Wu X, Kim S, McIntire K, Naini L, Hughes MD, Dawson R, Mave V, Gaikwad S, Sanchez J, Mendoza-Ticona A, Gonzales P, Comins K, Shenje J, Fontain SN, Omozoarhe A, Mohapi L, Lalloo UG, Garcia Ferreira AC, Mugah C, Harrington M, Shah NS, Hesseling AC, Churchyard G, Swindells S, Gupta A; AIDS Clinical Trials Group A5300/International Maternal Pediatric Adolescent AIDS Clinical Trials I2003 Protecting Households on Exposure to Newly Diagnosed Index Multidrug-resistant Tuberculosis Patients Feasibility Study Team* Clin Infect Dis. 2023 Sep 18;77(6):892-900. doi: 10.1093/cid/ciad301. PMID: 37227925; PMCID: PMC10681643.

A Mixture Model for Estimating SARS-CoV-2 Seroprevalence in Chennai, India
Hitchings MDT, Patel EU, Khan R, Srikrishnan AK, Anderson M, Kumar KS, Wesolowski AP, Iqbal SH, Rodgers MA, Mehta SH, Cloherty G, Cummings DAT, Solomon SS. Am J Epidemiol. 2023 Sep 1;192(9):1552-1561. doi: 10.1093/aje/kwad103. PMID: 37084085; PMCID: PMC10472327.

Pitavastatin to Prevent Cardiovascular Disease in HIV Infection
Grinspoon SK, Fitch KV, Zanni MV, Fichtenbaum CJ, Umbleja T, Aberg JA, Overton ET, Malvestutto CD, Bloomfield GS, Currier JS, Martinez E, Roa JC, Diggs MR, Fulda ES, Paradis K, Wiviott SD, Foldyna B, Looby SE, Desvigne-Nickens P, Alston-Smith B, Leon-Cruz J, McCallum S, Hoffmann U, Lu MT, Ribaudo HJ, Douglas PS; REPRIEVE Investigators. N Engl J Med. 2023 Aug 24;389(8):687-699. doi: 10.1056/NEJMoa2304146. Epub 2023 Jul 23. PMID: 37486775; PMCID: PMC10564556.

Respondent-driven sampling is more efficient than facility-based strategies at identifying undiagnosed people who inject drugs living with HIV in India
McFall AM, Solomon SS, Lau B, Latkin C, Srikrishnan AK, Anand S, Vasudevan CK, Kumar MS, Lucas GM, H Mehta S. Drug Alcohol Depend. 2023 Aug 1;249:110834. doi: 10.1016/j.drugalcdep.2023.110834. Epub 2023 Jun 16. PMID: 37352733; PMCID: PMC10330670.

Comparative immune responses to Mycobacterium tuberculosis in people with latent infection or sterilizing protection
Jalbert E, Liu C, Mave V, Lang N, Kagal A, Valvi C, Paradkar M, Gupte N, Lokhande R, Bharadwaj R, Kulkarni V, Gupta A, Weinberg A. iScience. 2023 Jul 20;26(8):107425. doi: 10.1016/j.isci.2023.107425. PMID: 37564701; PMCID: PMC10410524.

Maternal Colonization Versus Nosocomial Transmission as the Source of Drug-Resistant Bloodstream Infection in an Indian Neonatal Intensive Care Unit: A Prospective Cohort Study
Robinson ML, Johnson J, Naik S, Patil S, Kulkarni R, Kinikar A, Dohe V, Mudshingkar S, Kagal A, Smith RM, Westercamp M, Randive B, Kadam A, Babiker A, Kulkarni V, Karyakarte R, Mave V, Gupta A, Milstone AM, Manabe YC. Clin Infect Dis. 2023 Jul 5;77(Suppl 1):S38-S45. doi: 10.1093/cid/ciad282. PMID: 37406039; PMCID: PMC10321698.

Efficacy and safety of three antiretroviral therapy regimens started in pregnancy up to 50 weeks post partum: a multicentre, open-label, randomised, controlled, phase 3 trial
Chinula L, Ziemba L, Brummel S, McCarthy K, Coletti A, Krotje C, Johnston B, Knowles K, Moyo S, Stranix-Chibanda L, Hoffman R, Sax PE, Stringer J, Chakhtoura N, Jean-Philippe P, Korutaro V, Cassim H, Fairlie L, Masheto G, Boyce C, Frenkel LM, Amico KR, Purdue L, Shapiro R, Mmbaga BT, Patel F, van Wyk J, Rooney JF, Currier JS, Lockman S; IMPAACT 2010/VESTED Study Team and Investigators. Lancet HIV. 2023 Jun 15;10(6):e363-e374. doi: 10.1016/S2352-3018(23)00061-9. Epub 2023 May 8. PMID: 37167996; PMCID: PMC10280394.

Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the REMEMBER trial
Araújo-Pereira M, Krishnan S, Salgame P, Manabe YC, Hosseinipour MC, Bisson G, Severe DP, Rouzier V, Leong S, Mave V, Sawe FK, Siika AM, Kanyama C, Dadabhai SS, Lama JR, Valencia-Huamani J, Badal-Faesen S, Lalloo UG, Naidoo K, Mohapi L, Kityo C, Andrade BB, Gupta A. EClinicalMedicine. 2023 Jun 2;60:102030. doi: 10.1016/j.eclinm.2023.102030. PMID: 37287871; PMCID: PMC10242630.

Integration of a geospatially targeted community-based testing approach with respondent-driven sampling to identify people who inject drugs living with HIV and HCV in Patti and Gorakhpur, India
Loeb TA, McFall AM, Srikrishnan AK, Anand S, Vasudevan CK, Mehta SH, Solomon SS. Drug Alcohol Depend. 2023 Jun 1;247:109874. doi: 10.1016/j.drugalcdep.2023.109874. Epub 2023 Apr 14. PMID: 37087926; PMCID: PMC10612114.

QuantiFERON Supernatant-Based Host Biomarkers Predicting Progression to Active Tuberculosis Disease Among Household Contacts of Tuberculosis Patients
Daniel EA, Thiruvengadam K, Rajamanickam A, Chandrasekaran P, Pattabiraman S, Bhanu B, Sivaprakasam A, Paradkar M, Kulkarni V, Karyakarte R, Shivakumar SVBY, Mave V, Gupta A, Babu S, Hanna LE. Clin Infect Dis. 2023 May 24;76(10):1802-1813. doi: 10.1093/cid/ciac979. PMID: 36582115.

Swimming against the STREAM: Why STREAM 2 data cannot be easily applied to MDR-TB patients across India
Udwadia ZF, Patel JM, Batyala M, Tornheim JA, Rodrigues C. Lung India. 2023 May-Jun 15;40(3):290-291. doi: 10.4103/lungindia.lungindia_74_23. PMID: 37148033; PMCID: PMC10298808.

A multi-center, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction
Queiroz ATL, Vinhaes CL, Fukutani ER, Gupte AN, Kumar NP, Fukutani KF, Arriaga MB, Sterling TR, Babu S, Gaikwad S, Karyakarte R, Mave V, Paradhkar M, Viswanathan V, Gupta A, Andrade BB, Kornfeld H; RePORT Brazil; RePORT India Consortia. Sci Rep. 2023 May 12;13(1):7769. doi: 10.1038/s41598-023-34847-9. PMID: 37173394; PMCID: PMC10180618.

Buprenorphine treatment receipt characteristics and retention among people who inject drugs at Integrated Care Centers in India
Ganapathi L, McFall AM, Greco KF, Srikrishnan AK, Kumar MS, Mayer KH, O'Cleirigh C, Mehta SH, Lucas GM, Solomon SS. Drug Alcohol Depend. 2023 May 1;246:109839. doi: 10.1016/j.drugalcdep.2023.109839. Epub 2023 Mar 20. PMID: 37031487; PMCID: PMC10416117.

Challenges with the use of Xpert HPV as a screening tool for oral HPV among people living with HIV (PLHIV): experiences from Pune, India
Admase A, Joshi S, Borse R, Deshpande P, Kulkarni V, Khaire S, Thakur R, Chavan A, Nimkar S, Mave V, Marbaniang I. BMC Infect Dis. 2023 Apr 17;23(1):233. doi: 10.1186/s12879-023-08210-2. PMID: 37069524; PMCID: PMC10108491.

Impact of Undernutrition on Tuberculosis Treatment Outcomes in India: A Multicenter, Prospective, Cohort Analysis
Sinha P, Ponnuraja C, Gupte N, Prakash Babu S, Cox SR, Sarkar S, Mave V, Paradkar M, Cintron C, Govindarajan S, Kinikar A, Priya N, Gaikwad S, Thangakunam B, Devarajan A, Dhanasekaran M, Tornheim JA, Gupta A, Salgame P, Christopher DJ, Kornfeld H, Viswanathan V, Ellner JJ, Horsburgh CR, Gupte AN, Padmapriyadarsini C, Hochberg NS. Clin Infect Dis. 2023 Apr 17;76(8):1483-1491. doi: 10.1093/cid/ciac915. PMID: 36424864; PMCID: PMC10319769.

Sex Differences in TB Clinical Presentation, Drug Exposure, and Treatment Outcomes in India
Deshmukh S, Sane M, Gaikwad S, Sahasrabudhe T, Barthwal M, Lokhande R, Raskar S, Kagal A, Dharmshale S, Pradhan N, Gupte A, Alfarisi O, Gupta A, Dooley KE, Gupte N, Golub JE, Mave V. Chest. 2023 Apr 15;163(4):778-789. doi: 10.1016/j.chest.2022.09.024. Epub 2022 Sep 26. PMID: 36174745; PMCID: PMC10258435.

Mycobacterium tuberculosis disease associates with higher HIV-1-specific antibody responses
Adeoye B, Nakiyingi L, Moreau Y, Nankya E, Olson AJ, Zhang M, Jacobson KR, Gupta A, Manabe YC, Hosseinipour MC, Kumwenda J, Sagar M; AIDS Clinical Trials Group A5274 (REMEMBER) Study Team. iScience. 2023 Apr 10;26(5):106631. doi: 10.1016/j.isci.2023.106631. PMID: 37168567; PMCID: PMC10165194.

Effect of pregnancy versus postpartum maternal isoniazid preventive therapy on infant growth in HIV-exposed uninfected infants: a post-hoc analysis of the TB APPRISE trial
Cherkos AS, LaCourse SM, Enquobahrie DA, Richardson BA, Bradford S, Montepiedra G, Mmbaga BT, Mbengeranwa T, Masheto G, Jean-Phillippe P, Chakhtoura N, Theron G, Weinberg A, Cassim H, Raesi MS, Jean E, Wabwire D, Nematadzira T, Stranix-Chibanda L, Hesseling AC, Aurpibul L, Gupta A, John-Stewart G; IMPAACT P1078 TB APPRISE Study Team. EClinicalMedicine. 2023 Mar 17;58:101912. doi: 10.1016/j.eclinm.2023.101912. PMID: 36969345; PMCID: PMC10031034.

Factors associated with prevalent Mycobacterium tuberculosis infection and disease among adolescents and adults exposed to rifampin-resistant tuberculosis in the household
Kim S, Hesseling AC, Wu X, Hughes MD, Shah NS, Gaikwad S, Kumarasamy N, Mitchell E, Leon M, Gonzales P, Badal-Faesen S, Lourens M, Nerette S, Shenje J, de Koker P, Nedsuwan S, Mohapi L, Chakalisa UA, Mngqbisa R, Escada RODS, Ouma S, Heckman B, Naini L, Gupta A, Swindells S, Churchyard G; ACTG A5300/IMPAACT 2003 PHOENIx Feasibility Study Team. PLoS One. 2023 Mar 17;18(3):e0283290. doi: 10.1371/journal.pone.0283290. PMID: 36930628; PMCID: PMC10022776.

Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis
Gafar F, Wasmann RE, McIlleron HM, Aarnoutse RE, Schaaf HS, Marais BJ, Agarwal D, Antwi S, Bang ND, Bekker A, Bell DJ, Chabala C, Choo L, Davies GR, Day JN, Dayal R, Denti P, Donald PR, Engidawork E, Garcia-Prats AJ, Gibb D, Graham SM, Hesseling AC, Heysell SK, Idris MI, Kabra SK, Kinikar A, Kumar AKH, Kwara A, Lodha R, Magis-Escurra C, Martinez N, Mathew BS, Mave V, Mduma E, Mlotha-Mitole R, Mpagama SG, Mukherjee A, Nataprawira HM, Peloquin CA, Pouplin T, Ramachandran G, Ranjalkar J, Roy V, Ruslami R, Shah I, Singh Y, Sturkenboom MGG, Svensson EM, Swaminathan S, Thatte U, Thee S, Thomas TA, Tikiso T, Touw DJ, Turkova A, Velpandian T, Verhagen LM, Winckler JL, Yang H, Yunivita V, Taxis K, Stevens J, Alffenaar JC; Global Collaborative Group for Meta-Analysis of Paediatric Individual Patient Data in Pharmacokinetics of Anti-TB Drugs. Eur Respir J. 2023 Mar 9;61(3):2201596. doi: 10.1183/13993003.01596-2022. PMID: 36328357; PMCID: PMC9996834.

Higher Dose Oral Fluconazole for the Treatment of AIDS-related Cryptococcal Meningitis (HIFLAC)-report of A5225, a multicentre, phase I/II, two-stage, dose-finding, safety, tolerability and efficacy randomised, amphotericin B-controlled trial of the AIDS Clinical Trials Group
Lalloo UG, Komarow L, Aberg JA, Clifford DB, Hogg E, McKhann A, Bukuru A, Lagat D, Pillay S, Mave V, Supparatpinyo K, Samaneka W, Langat D, Ticona E, Badal-Faesen S, Larsen RA; ACTG A5225 Team. PLoS One. 2023 Feb 13;18(2):e0281580. doi: 10.1371/journal.pone.0281580. PMID: 36780493; PMCID: PMC9925064.

"Mobilizing our leaders": A multi-country qualitative study to increase the representation of women in global health leadership
Riche CT, Reif LK, Nguyen NT, Alakiu GR, Seo G, Mathad JS, McNairy ML, Cordeiro AA, Kinikar A, Walsh KF, Deschamps MM, Nerette S, Nimkar S, Kayange N, Jaka H, Mwaisungu HM, Morona D, Peter TY, Suryavanshi N, Fitzgerald DW, Downs JA, Hokororo A. PLOS Glob Public Health. 2023 Jan 30;3(1):e0000646. doi: 10.1371/journal.pgph.0000646. PMID: 36962949; PMCID: PMC10021821.

Prevalence of neurotoxicity symptoms among postpartum women on isoniazid preventive therapy and efavirenz-based treatment for HIV: an exploratory objective of the IMPAACT P1078 randomized trial
Mandima P, Baltrusaitis K, Montepiedra G, Aaron L, Mathad J, Onyango-Makumbi C, Nyati M, Ngocho J, Chareka G, Ponatshego P, Masheto G, McCarthy K, Jean-Philippe P, Gupta A, Stranix-Chibanda L; IMPAACT P1078 T. B. APPRISE study team. BMC Pregnancy Childbirth. 2023 Jan 17;23(1):34. doi: 10.1186/s12884-022-05341-3. PMID: 36650479; PMCID: PMC9847058.

Pharmacokinetic analysis of linezolid for multidrug resistant tuberculosis at a tertiary care centre in Mumbai, India
Resendiz-Galvan JE, Arora PR, Abdelwahab MT, Udwadia ZF, Rodrigues C, Gupta A, Denti P, Ashavaid TF, Tornheim JA. Front Pharmacol. 2023 Jan 4;13:1081123. doi: 10.3389/fphar.2022.1081123. PMID: 36686664; PMCID: PMC9846493.

Self-reported Antiretroviral Adherence: Association With Maternal Viral Load Suppression in Postpartum Women Living With HIV-1 From Promoting Maternal and Infant Survival Everywhere, a Randomized Controlled Trial in Sub-Saharan Africa and India
Nevrekar N, Butler K, Shapiro DE, Atuhaire P, Taha TE, Makanani B, Chinula L, Owor M, Moodley D, Chipato T, McCarthy K, Flynn PM, Currier J, Fowler MG, Gupta A, Suryavanshi N. J Acquir Immune Defic Syndr. 2023 Jan 1;92(1):76-83. doi: 10.1097/QAI.0000000000003102. Epub 2022 Sep 28. PMID: 36170749; PMCID: PMC9722360.


Learn More