2025 Publications

Explore our research findings.


Maternal anemia during pregnancy and its association with the gut microbiota profile in pregnant and postpartum women, and their infants: a cohort study.  

Mandell J, Caulfield LE, Talegawkar S, Mathad JS, Naik S, Alexander M, Shafiq M, Kulkarni V, Deshpande P, Mao YM, Humphreys MS, Ma B, Holm JB, Bhosale R, Ghanem KG, Kinikar A, Wang T, Wang S, Ravel J, Gupta A, Shivakoti R. Am J Clin Nutr. 2025 Sep 25:S0002-9165(25)00586-6. doi: 10.1016/j.ajcnut.2025.09.035. Epub ahead of print. PMID: 41015193. 

Protecting households on exposure to newly diagnosed index multidrug-resistant tuberculosis patients: Study protocol for the PHOENIx phase 3 clinical trial. 

Kendall MA, Hughes MD, Kim S, Aaron LA, Naini L, Suryavanshi N, Shah NS, Rouzier V, Hafkin J, Sise T, Beck J, Heckman BE, Haberer JE, Harrington M, Scarsi KK, Hesseling AC, Swindells S, Churchyard GJ, Gupta A. Contemp Clin Trials. 2025 Sep 22;158:108084. doi: 10.1016/j.cct.2025.108084. Epub ahead of print. PMID: 40992540. 

The Effectiveness of Isoniazid Preventive Treatment among Contacts of Multidrug-Resistant Tuberculosis: A Systematic Review and Individual-Participant Meta-Analysis.  

Martinez L, Campbell JI, Linde L, Boulahbal F, Cayla JA, Chakhaia T, Chan PC, Chen C, Fang CT, Fox G, Grandjean L, Hannoun D, Hesseling A, Horsburgh CR, Huang LM, Liu Q, Mazahir R, Lee CH, Lee LN, Bennet R, Nejat S, Gupta A, Das M, Murray M, Huang CC, Del Corral H, Benjumea-Bedoya D, Shen Y, Becerra M, Chang V, Krishnan S, Heinmueller P, Brewer T, Isaakidis P, Hauri AM, Shah L, Trieu L, Seddon JA. Am J Respir Crit Care Med. 2025 Sep 23. doi: 10.1164/rccm.202411-2340OC. Epub ahead of print. PMID: 40986702.  

Predictive metabolite signatures for risk of progression to active TB from QuantiFERON supernatants of household contacts of TB patients.

Daniel EA, Upadhyay S, Selvachithiram M, Pattabiraman S, Bhanu B, Sivaprakasam A, Kulkarni V, Karyakarte R, Gaikwad S, Paradkar M, Yogendra Shivakumar SVB, Mave V, Gupta A, Prasad K, Hanna LE.Emerg Microbes Infect. 2025 Dec;14(1):2437242. doi: 10.1080/22221751.2024.2437242. Epub 2024 Dec 22. PMID: 39628384 

Contribution of Key Comorbidities to Unfavorable Treatment Outcomes among Adults with Drug-sensitive Pulmonary Tuberculosis in India: a Prospective Cohort Analysis.

Sinha P, Karoly M, Padmapriyadarsini C, Paradkar M, Mave V, Gupte N, Gupta A, Dauphinais M, Babu SP, Gaikwad S, Cox SR, Golub J, Cintron C, Thangakunam B, Ezhumalai K, Ponnuraja C, Tornheim JA, Christopher DJ, Viswanathan V, Ellner JJ, Kornfeld H, Horsburgh CR Jr, Bala Yogendra Shivakumar SV, Salgame P, Bollinger RC, Sarkar S, Gupte AN; RePORT-India TB Research Consortium.Chest. 2025 Sep 10:S0012-3692(25)05171-2. doi: 10.1016/j.chest.2025.05.055. Online ahead of print. PMID: 40939932

A 3-month clofazimine-rifapentine-containing regimen for drug-susceptible tuberculosis versus standard of care (Clo-Fast): a randomised, open-label, phase 2c clinical trial.

Metcalfe JZ, Weir IR, Scarsi KK, Mendoza-Ticona A, Pierre S, Hall L, Leon-Cruz J, Svensson EM, Koele SE, Samaneka W, Kanyama C, Yohane M, Nevrekar N, Ntsalaze B, Marc JB, Goth M, Maartens G, Chaisson R; ACTG A5362 study team.Lancet Infect Dis. 2025 Sep 4:S1473-3099(25)00436-0. doi: 10.1016/S1473-3099(25)00436-0. Online ahead of print. PMID: 40915311 

Evaluation of cycloserine dose regimens in an Indian cohort with multidrug-resistant tuberculosis: a population pharmacokinetic analysis.

Resendiz-Galvan JE, Arora PR, Lokhande RV, Udwadia ZF, Rodrigues C, Gupta A, Tornheim JA, Denti P, Ashavaid TF; The MDR-TB MUKT and Indo-South Africa Study Teams; MDR-TB MUKT and Indo-South Africa Study Teams.Antimicrob Agents Chemother. 2025 Sep 2:e0010125. doi: 10.1128/aac.00101-25. Online ahead of print. PMID: 40891988 

The role of financial stress, food insecurity, and COVID-19-related illness concerns shaping mental health in five South Asian countries during the pandemic (2020-2022): A secondary analysis of the online COVID-19 Trends and Impact Survey (CTIS) data.

Yang Y, Zimmermann L, Pramanik S, Wahl B, Mukherjee B.PLOS Glob Public Health. 2025 Aug 8;5(8):e0004704. doi: 10.1371/journal.pgph.0004704. eCollection 2025. PMID: 40779535 

Improving Treatment Adherence in Youths With Multidrug-Resistant Tuberculosis With Psychosocial Intervention.

Dhumal G, Nevrekar N, Gupte N, Shrisunder R, Kulkarni P, Sarpotdar S, Pm A, Hosmani A, Lokhande R, Gupta A, Suryavanshi N.Brain Behav. 2025 Aug;15(8):e70665. doi: 10.1002/brb3.70665. PMID: 40760794 

Syndemic vulnerability for suicidal ideations among youth with and without HIV in India: a latent class approach.

Gill A, Stojanovoski K, Theall KP, Borse R, Nimkar S, Gupta A, Mave V, Suryavanshi N.AIDS Care. 2025 Aug;37(8):1292-1301. doi: 10.1080/09540121.2025.2534123. Epub 2025 Jul 30. PMID: 40739717 

USAID's Role in Saving Children's Lives: Past Legacy and Future Directions.

Coria AL, Wahl B, Thacker N, Vreeman R, Zühlke L.Pediatrics. 2025 Aug 1;156(2):e2025071260. doi: 10.1542/peds.2025-071260. PMID: 40268761 

Multicohort assessment of plasma metabolic signatures of tuberculosis disease in children.

Nellis MM, Luiz J, Jaganath D, Mousavian Z, Nkereuwem E, Wambi P, Calderon R, Paradkar M, Castro R, Nerurkar R, Franke MF, Kinikar A, Wobudeya E, Zar HJ, Segal M, Sigal G, Swaney DL, Cattamanchi A, Ernst JD, Ziegler TR, Kampmann B, Collins JM.Res Sq [Preprint]. 2025 Jul 29:rs.3.rs-7086994. doi: 10.21203/rs.3.rs-7086994/v1. PMID: 40766222 

A point-of-care prediction tool for recurrent tuberculosis.

Cox SR, Moe AH, Gupte AN, Kadam A, Valawalkar S, Gupte N, Lele G, Kendall EA, Baillie C, Barthwal MS, Kakrani A, Mave V, Dowdy DW, Golub JE.Clin Infect Dis. 2025 Jul 8:ciaf353. doi: 10.1093/cid/ciaf353. Online ahead of print. PMID: 40626664

Population pharmacokinetics and dosing of dispersible moxifloxacin formulation in children with rifampicin-resistant tuberculosis.
Palmer M, Zou Y, Hesseling AC, van der Laan L, Courtney I, Kinikar AA, Sonkawade N, Paradkar M, Kulkarni V, Casalme DJO, Frias MVG, Draper H, Wiesner L, Karlsson MO, Denti P, Svensson EM, Garcia-Prats AJ.Br J Clin Pharmacol. 2025 Jun;91(6):1853-1864. doi: 10.1111/bcp.70005.PMID: 40441696 

Tuberculosis disease among people with HIV: therapeutic advances.
Mave V, Paradkar M, Conradie F, Gupta A, Avihingsanon A, Meintjes G, Turkova A, Dooley KE, Chaisson RE.Lancet HIV. 2025 May;12(5):e367-e381. doi: 10.1016/S2352-3018(25)00040-2. Epub 2025 Mar 24.PMID: 40147460 

Preferences and Feasibility of Long-Acting Technologies for the Treatment of Hepatitis C Virus: A Survey of Patients in Diverse Low- and Middle-Income Countries.
Furl R, Scarsi KK, Sayles H, Anderson M, Ofimboudem JD, Weld ED, Waked I, Gomaa A, Al-Khatib A, Elshobary FM, Desalegn H, Fisseha H, Solomon S, Mehta S, Owen A, Rannard S, Thomas DL, Swindells S.J Viral Hepat. 2025 Apr;32(4):e14031. doi: 10.1111/jvh.14031. Epub 2024 Nov 15.PMID: 39545599 

Addressing post-tuberculosis sequelae among people living with HIV: an unmet need.
Mave V, Cox SR, Gupte AN, Golub JE.J Int AIDS Soc. 2025 Mar;28(3):e26439. doi: 10.1002/jia2.26439.PMID: 40123373 

Plasma Immune Biomarkers Predictive of Progression to Active Tuberculosis in Household Contacts of Patients With Tuberculosis.
Rajamanickam A, Ann Daniel E, Dasan B, Thiruvengadam K, Chandrasekaran P, Gaikwad S, Pattabiraman S, Bhanu B, Sivaprakasam A, Kulkarni V, Karyakarte R, Paradkar M, Shivakumar SVBY, Mave V, Gupta A, Hanna LE, Babu S.J Infect Dis. 2025 Mar 17;231(3):696-705. doi: 10.1093/infdis/jiae365.PMID: 39028003

Risk Factors for Health Care-Associated Bloodstream Infections in NICUs.
Johnson J, Malwade S, Agarkhedkar S, Randive B, Rajput UC, Valvi C, Kinikar A, Parikh TB, Vaidya U, Kadam A, Ouddi B, Smith RM, Westercamp M, Mave V, Schumacher C, Coffin SE, Robinson ML, Gupta A, Manabe YC, Milstone AM.JAMA Netw Open. 2025 Mar 3;8(3):e251821. doi: 10.1001/jamanetworkopen.2025.1821.PMID: 40131271 

Does knowledge impact adherence?: correlation between HIV-infected pregnant women's knowledge of WHO-recommended PMTCT guidelines and their adherence to the PMTCT program in India.
Bagchi S, Kadam A, Mave V, Shankar A, Kanade S, Deoraj P, McKenzie-White J, Gupta A, Gupte N, Bollinger RC, Suryavanshi N.AIDS Care. 2025 Mar;37(3):469-479. doi: 10.1080/09540121.2025.2452520. Epub 2025 Jan 20.PMID: 39832305

Drug Resistance and Epidemiological Success of Modern Mycobacterium tuberculosis Lineages in Western India.
Dixit A, Ektefaie Y, Kagal A, Freschi L, Karyakarte R, Lokhande R, Groschel M, Tornheim JA, Gupte N, Pradhan NN, Paradkar MS, Deshmukh S, Kadam D, Schito M, Engelthaler DM, Gupta A, Golub J, Mave V, Farhat M.J Infect Dis. 2025 Feb 4;231(1):84-93. doi: 10.1093/infdis/jiae240.PMID: 38819323 

Population pharmacokinetics and dosing of dispersible moxifloxacin formulation in children with rifampicin-resistant tuberculosis.
Palmer M, Zou Y, Hesseling AC, van der Laan L, Courtney I, Kinikar AA, Sonkawade N, Paradkar M, Kulkarni V, Casalme DJO, Frias MVG, Draper H, Wiesner L, Karlsson MO, Denti P, Svensson EM, Garcia-Prats AJ.Br J Clin Pharmacol. 2025 Feb 17. doi: 10.1002/bcp.70005. Online ahead of print.PMID: 39957395

Tuberculosis Preventive Treatment in High TB-Burden Settings: A State-of-the-Art Review.
Chihota V, Gombe M, Gupta A, Salazar-Austin N, Ryckman T, Hoffmann CJ, LaCourse S, Mathad JS, Mave V, Dooley KE, Chaisson RE, Churchyard G.Drugs. 2025 Feb;85(2):127-147. doi: 10.1007/s40265-024-02131-3. Epub 2024 Dec 28.PMID: 39733063 

HIV-related Differences in Placental Immunology: Data From the PRACHITi Cohort in Pune, India.
Mathad JS, Alexander M, Bhosale R, Naik S, Cranmer LM, Kulkarni V, Busch S, Chalem A, Gitlin E, Lei J, Liu A, Liu J, Liu Y, Shivakoti R, Gupta A, Burd I.Open Forum Infect Dis. 2025 Jan 31;12(3):ofaf047. doi: 10.1093/ofid/ofaf047. eCollection 2025 Mar.PMID: 40046890 

Treatment outcomes among children and adolescents with extensively drug-resistant (XDR) and pre-XDR tuberculosis: Systematic review and meta-analysis.
Patra J, Irving H, Maini P, Liang J, Patra A, Paradkar M, Rehm J.PLOS Glob Public Health. 2025 Jan 29;5(1):e0003754. doi: 10.1371/journal.pgph.0003754. eCollection 2025.PMID: 39879191 

Piloting an event-based surveillance model in private hospitals for early detection of disease clusters, Kerala, India.
Vaman RS, Solomon S, Averhoff F, Landay AL, Thangaraj JWV, Abdulkader RS, Joseph F, Cloherty G, Murhekar MV.Indian J Med Res. 2025 Jan;161(1):54-63. doi: 10.25259/IJMR_1395_2024.PMID: 40036102 

Predictive Markers of Incident Tuberculosis in Close Contacts in Brazil and India.
Nogueira BMF, Rangel F, Andrade AMS, Daniel EA, Figueiredo MC, Staats C, Rolla VC, Kritski AL, Cordeiro-Santos M, Gupta A, Hanna LE, Sterling TR, Araújo-Pereira M, Andrade BB; RePORT Brazil and RePORT India Consortia.J Infect Dis. 2025 Jan 7:jiae642. doi: 10.1093/infdis/jiae642. Online ahead of print.PMID: 39763217

Long-term risk of mortality and loss to follow-up in children and adolescents on antiretroviral therapy in Asia.
Nimkar S, Kinikar A, Mave V, Khol V, Du QT, Nguyen L, Ounchanum P, Nguyen DQ, Puthanakit T, Kosalaraks P, Chokephaibulkit K, Sudjaritruk T, Muktiarti D, Kumarasamy N, Yusoff NKN, Mohamed T, Wati D, Alam A, Fong S, Nallusamy R, Suwanlerk T, Sohn A, Kariminia A; TREAT Asia Pediatric HIV Observational Database of IeDEA Asia‐Pacific.HIV Med. 2025 Jan;26(1):140-152. doi: 10.1111/hiv.13718. Epub 2024 Sep 26.PMID: 39324422

Discordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India.
Kulkarni V, Alexander M, Bhosale R, Jain D, Deshpande P, Gitlin ES, Vaidyanathan A, Chalem A, Naik S, Gupte N, Nawani N, Gupta A, Mathad J.J Clin Tuberc Other Mycobact Dis. 2024 Dec 4;38:100504. doi: 10.1016/j.jctube.2024.100504. eCollection 2025 Feb.PMID: 39758562 


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