Publications - Disease diagnosis

Linezolid resistance mycobacterium tuberculosis isolates at a tertiary center in Mumbai, India

Post Date:

2021-07-01

Countries:

Publication:

Indian Journal of Medical Research

Background & objectives: Linezolid (LZD) is increasingly being used in tuberculosis (TB) treatment. However, LZD resistance has already been reported, which is highly alarming, given its critical therapeutic role. This study was aimed to phenotypically and genotypically assess LZD resistance in...

Tuberculosis preventive treatment should be considered for all household contacts of pulmonary tuberculosis patients in India

Post Date:

2020-07-29

Countries:

India

Clinical Sites:

BJGMC

Publication:

PLoS One

PLoS One: Dr. Mandar Paradkar and colleagues conducted a CTRIUMPH study that supports TB preventive therapy for all household contacts of pulmonary TB patients in India

A mobile health-facilitated behavioral intervention for community health workers improves exclusive breastfeeding and early infant HIV diagnosis in India: A cluster randomized trial

Post Date:

2020-07-03

Countries:

India

Clinical Sites:

BJGMC

Publication:

Journal of the International AIDS Society

When community health workers used a mobile health intervention with HIV+ women to deliver care, there was a higher uptake of exclusive breastfeeding at two months and early infant HIV diagnosis at six weeks

Trends and gender differences in access to HIV care with scale up of national HIV treatment guidelines in India

Post Date:

2020-06-24

Countries:

India

Publication:

Journal of the International Association of Providers of AIDS Care

Test and treat is the current global standard, yet sex differences persist in access to HIV care. We assessed the differences in presentation and antiretroviral therapy (ART) uptake by sex and ART-eligibility period among ART-naive adults registered at a public ART center in India. Four ART...

Intensified short symptom screening program for Dengue infection during pregnancy, India

Post Date:

2020-04-15

Countries:

India

Clinical Sites:

BJGMC

Publication:

Emerging Infectious Diseases

Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017-January 2018, we screened pregnant...

TB prevention strategies and unanswered questions for pregnant and postpartum women living with HIV: the need for improved evidence

Post Date:

2020-03-23

Publication:

Journal of the International AIDS Society

World TB Day viewpoint on the need for more data about TB treatment for pregnant and postpartum women in J Int AIDS Soc by Drs. Jyoti Mathad and Amita Gupta.

Assessment of the Xpert assay among new pulmonary tuberculosis suspects with and without diabetes mellitus

Post Date:

2020-01-01

Clinical Sites:

BJGMC

Publication:

International Journal of Tuberculosis and Lung Disease

IJTLD: Deshmukh and colleagues: High sensitivity and specificity of Xpert underscores need for rapid scale up for early detection of TB in settings with a high dual burden of TB and DM

Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study

Post Date:

2019-07-29

Countries:

India

Clinical Sites:

BJGMC

Publication:

Lancet HIV

BACKGROUND: Antiretroviral therapy (ART) management is challenging for individuals in resource-limited settings presenting for third-line treatment because of complex resistance patterns, partly due to reduced access to viral load monitoring. We aimed to evaluate use of newer...

Users beware! Biological variation in complete blood counts over short time intervals

Post Date:

2019-05-29

Publication:

BMJ Evidence Based Medicine

New publication in BMJ Evidence Based Medicine looks at CBC count variations in blood drawn over a short time period

Symptom screening for active tuberculosis in pregnant women living with HIV

Post Date:

2019-01-24

Publication:

Cochrane Database of Systematic Reviews

This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: To assess the accuracy of the four-symptom screen (cough, fever, night sweats, or weight loss) for identifying active TB in pregnant PLHIV who are screened in an outpatient or community setting...

HIV testing uptake among the household contacts of multidrug-resistant tuberculosis index cases in eight countries

Post Date:

2019-01-07

Countries:

India

Clinical Sites:

BJGMC

Publication:

International Journal of Tuberculosis and Lung Disease

International Journal of Tuberculosis and Lung Disease : The Indo-JHU Clinical Research Parentership participated in this multinational study to determine if it's feasible to provide HIV testing for household contacts of MDR-TB cases.

Atypical mycobacterial infections following plastic surgery procedures abroad: a multidisciplinary algorithm for diagnosis and treatment

Post Date:

2018-12-28

Abstract: Medical tourism has become increasingly popular in recent years. The most commonly sought procedures are cosmetic. The recent rise in medical tourism has been mirrored by an increase in the incidence of M. abscessus infections, atypical mycobacteria ubiquitous in aquatic environments...

Multiplex-PCR to detect pAmpC β-lactamases among Enterobacteriaceae at a tertiary care laboratory in Mumbai, India

Post Date:

2018-12-13

Countries:

India

Clinical Sites:

Hinduja Hospital

Publication:

Microbiology

Drug-resistance due to AmpC β-lactamases represents a growing problem worldwide. In this study, a previously collected sample of 108 cefoxitin-resistant clinical isolates was assessed for AmpC β-lactamase production through routine phenotypic testing and double-disc cefoxitin/cloxcallin (DD-CC),...

Barriers to screening and isoniazid preventive therapy for child contacts of tuberculosis patients

Post Date:

2018-10-01

Countries:

India

Clinical Sites:

BJGMC

Publication:

International Journal of Tuberculosis and Lung Disease

Universal, timely TB screening and IPT for exposed children are urgently needed to reduce pediatric TB in India

Ovarian mass - tuberculosis or malignancy? Need for early intensified evaluation

Post Date:

2018-09-14

Countries:

India

Clinical Sites:

BJGMC

Publication:

EXCLI Journal

Letter to the Editor Dear Editor, We read with interest the case report by Chien et al. on Peritoneal Tuberculosis (TB) mimicking ovarian cancer (Chien et al., 2016[1]). We want to congratulate the authors on this case report. We encountered a similar case in our clinical setting in western India...

Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India

Post Date:

2018-05-02

Countries:

India

Clinical Sites:

BJGMC

Publication:

Clinical Infectious Diseases

Mosquito-borne disease identification is associated with reduced empiric antibiotic use and faster antibiotic discontinuation.

Pyrosequencing to resolve discrepant Xpert MTB/RIF and Mycobacterial Growth Indicator Tube 960

Post Date:

2018-03-26

Countries:

India

Clinical Sites:

Hinduja Hospital

Publication:

Lung India

Lung India: Indo-JHU researchers find that pyrosequencing can clear up discrepancies about drug resistance in TB.

A qualitative study exploring factors influencing clinical decision-making for influenza-like illness in Solapur city, Maharashtra, India

Post Date:

2017-07-03

Countries:

India

Publication:

Anthropology and Medicine

Abstract The co-existence of different types of medical systems (medical pluralism) is a typical feature of India's healthcare system. For conditions such as influenza-like illness (ILI), where non-specific disease signs/symptoms exist, clinical reasoning in the context of medical...

Presence of human hepegivirus-1 in a cohort of people who inject drugs

Post Date:

2017-06-07

Publication:

Annals of Internal Medicine

Findings on the sensitivity of next-generation metagenomic sequencing for discovery of new viral infections.

Tuberculosis screening among persons with diabetes mellitus in Pune, India

Post Date:

2017-06-02

Countries:

India

Clinical Sites:

BJGMC

Publication:

BMC Infectious Diseases

Background: Diabetes mellitus (DM) increases tuberculosis (TB) risk, and there is increasing concern over the public health implications of the convergence of these two epidemics. Screening for TB among people with DM is now recommended in India. Methods: People with DM seeking...

Publications - Disease diagnosis

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