Characterization of Pulmonary and Extrapulmonary Tuberculosis Among Adult Patients Admitted to Sassoon General Hospital, Pune, India

Post Date: 
Clinical Sites: 
This study was terminated September 21, 2012. 
The diagnosis of pulmonary and extrapulmonary tuberculosis is usually made clinically. While confirmation from laboratory tests is sought, the sensitivity of such diagnostic tests is poor. TB diagnostics are still evolving and in resource poor settings diagnostic availabilty is limited. Therefore, it is important to understand factors associated with unsuccesful outcomes among patients diagnosed with pulmonary and extrapulmonary tuberculosis
To characterize the demographic, clinical characteristics and outcomes among patients hospitalized for pulmonary and extrapulmonary tuberculosis at Sassoon General Hospital.
Study Rationale:
Understanding the risk factors associated with TB and with poor outcomes in TB will be important for successfully reducing the burden of TB in India and in the state of Maharashtra. The diagnosis of pulmonary and extrapulmonary TB is usually made clinically because the sensitivity of laboratory tests is poor. TB diagnostic techniques are still evolving and their availability is limited in resource poor settings. Therefore, there is a pressing need to characterize the clinical and demographic characteristics associated with TB and with unsuccessful outcomes following treatment. Systematic identification of the risk factors associated with death and relapse and other severe complications in TB will prove valuable to physicians.