Modifiable risk factors associated with tuberculosis disease in children in Pune, India

Post Date: 
2014-02-15
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Publication: 
International Journal of Tuberculosis and Lung Disease
Summary: 

Setting: India accounts for the largest burden of tuberculosis (TB) worldwide, with 26% of the world's cases.


 


Objective: To assess the association between novel modifiable risk factors and TB in Indian children.


 


Design: Cases were children aged ≤ 5 years with confirmed/probable TB based on World Health Organization definitions (definition 1). Controls were healthy children aged ≤ 5 years. Logistic regression was performed to estimate the adjusted odds ratio (aOR) of being a TB case given exposure, including indoor air pollution (IAP; exposure to tobacco smoke and/or biomass fuels) and vitamin D deficiency. Cases were re-analyzed according to a new consensus research definition of pediatric TB (definition 2).

Citation: 
Jubulis J, Kinikar A, Ithape M, Khandave M, Dixit S, Hotalkar S, Kulkarni V, Mave V, Gupte N, Kagal A, Jain S, Bharadwaj R, Gupta A. Modifiable risk factors associated with tuberculosis disease in children in Pune, India. Int J Tuberc Lung Dis. 2014;18(2):198-204; doi: 10.5588/ijtld.13.0314. PMID: 24429313 .
Collaborators: 
  • Maine Medical Center, Portland, ME
  • BJGMC, Pune, India