Neeta Pradhan

Pune, India
Role: 
Staff
Tuberculosis Laboratory Coordinator
Neeta Pradhan headshot

Neeta Pradhan is a Medical Microbiologist holding a post graduate degree in Medical Microbiology (MSc- Medical Microbiology) and working in the laboratory field for more than 25 years with a total experience of more than 15 years in the Clinical Research field.

She has worked as a Laboratory Coordinator at NARI (National AIDS Research Institute) Clinical Trial Unit for various NIH projects like-- HIV Prevention Trials Network (HPTN), - AIDS Clinical Trial Group (ACTG), - Microbicide Trial Network (MTN).

She has also handled Indian Council of Medical Research (ICMR) projects.

She is currently working as a TB Laboratory Manager at Center of Infectious Diseases -India (CIDI) in Pune, India to overlook all the work that is carried out at the BJMC- CTU CRS site as well as all the other sites that collaborate with JHU. She is responsible and gives technical and TB laboratory support for all the TB network studies for ACTG/IMPACCT (International Maternal Pediatric Adolescent AIDS Clinical Trials Network) as well as all the non-network studies (collaborations with various international /national universities & institutions) conducted at BJMC site.

Besides International Network protocols she also provides TB lab support for NIH, USA-DBT, India funded Adult (CTRIUMPh, RePORT) and NICHD funded Pediatric TB (TBM Kids Trial) studies and is also involved in TB vaccine trial (VPM 1002) funded by Serum Institute, India and the Shorter Treatment for Minimal TB in Children (SHINE)trial funded by Joint Global Health Trials Scheme of the Department for International Development, UK, the Welcome Trust, and the Medical Research Council at the University College London, UK.

As a Laboratory person and Clinical researcher, she has worked on the pediatric TB meningitis treatment trial and observational TB cohort studies. As a part of the observational TB cohorts, also participated in studying the nutritional, clinical, diagnostic correlates and advanced biomarkers for TB disease and infection in the pediatric population. She has worked on studies on pregnant women in collaboration with NICHD.

She has completed the “Multicenter Study of the Accuracy of the BD MAX™ MDR-TB assay for Detection of M. tuberculosis Complex and Mutations Associated with Resistance to Rifampin and Isoniazid” which was done in collaboration with NIH and Becton Dickinson Company.

She is a member of the RePORT Consortium laboratory working group, the Basic Science group, as well as a Voting member of the Laboratory Technologist Committee (ACTG) studies involving TB and pregnant/non pregnant women with or without HIV.

Besides providing technical support to the clinical trials she also manages the laboratory which includes overseeing the daily activities as well as quality management, SOP writing, training of staff facing audits, overseeing the external Quality Assurance programs to name but a few.

Respiratory health status is associated with treatment outcomes in pulmonary tuberculosis

Post Date: 
2019-04-19
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The International Journal of Tuberculosis and Lung Disease
BACKGROUND: The association between respiratory impairment and tuberculosis (TB) treatment outcomes is not clear. METHODS: We prospectively evaluated respiratory health status, measured using the Saint George's Respiratory Questionnaire (SGRQ), in a cohort of new adult pulmonary TB cases during and...

The association of household fine particulate matter and kerosene with tuberculosis in women and children in Pune, India

Post Date: 
2018-09-07
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Occupational and Environmental Medicine
Use of kerosene cooking fuel is positively associated with TB in women and children in our analysis using reported sources of exposure.

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting

Post Date: 
2018-08-01
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PLoS One
World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

Post Date: 
2018-07-01
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International Journal of Tuberculosis and Lung Disease
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months,...

Diabetes and prediabetes among household contacts of tuberculosis patients in India: Is it time to screen them all?

Post Date: 
2018-06-01
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International Union Against Tuberculosis and Lung Disease
SETTING: Pre-diabetes mellitus (pre-DM) and DM increase the risk of developing tuberculosis (TB). Screening contacts of TB patients for pre-DM/DM and linking them to care may mitigate the risk of developing TB and improve DM management. OBJECTIVE: To measure the prevalence of pre-DM/DM and...

Diabetes and pre-diabetes among household contacts of tuberculosis patients in India: is it time to screen them all?

Post Date: 
2018-05-22
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The International Journal of Tuberculosis and Lung Disease
Authors find that screening contacts of TB patients for pre-DM/DM and linking them to care may mitigate the risk of developing tuberculosis and improve management of diabetes.

Prevalence of dysglycemia and clinical presentation of pulmonary tuberculosis in Western India

Post Date: 
2017-12-01
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International Journal of Tuberculosis and Lung Disease
Objectives: To estimate the prevalence and risk factors of pre-diabetes mellitus (DM) and DM, and its associations with the clinical presentation of tuberculosis (TB). Design: Screening for DM was conducted among adults (age  18 years) with confirmed TB between December 2013 and...

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH): protocol for a multicentric prospective observational study

Post Date: 
2016-02-25
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BMJ Open
Introduction: Tuberculosis disease (TB) remains an important global health threat. An evidence-based response, tailored to local disease epidemiology in high-burden countries, is key to controlling the global TB epidemic. Reliable surrogate biomarkers that predict key active disease and...

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