High rates of all-cause and gastroenteritis-related hospitalization morbidity and mortality among HIV-exposed Indian infants

Post Date:

2011-07-15

Countries:

India

Clinical Sites:

BJGMC

Publication:

BMC Infectious Diseases

Summary:

Background: HIV-infected and HIV-exposed, uninfected infants experience a high burden of infectious morbidity and mortality. Hospitalization is an important metric for morbidity and is associated with high mortality, yet, little is known about rates and causes of hospitalization among these infants in the first 12 months of life.

Methods: Using data from a prevention of mother-to-child transmission (PMTCT) trial (India SWEN), where HIV-exposed breastfed infants were given extended nevirapine, we measured 12-month infant all-cause and cause-specific hospitalization rates and hospitalization risk factors.

Citation:

Bollinger RC, Gupta A and the SWEN India Study Team. High rates of all-cause and gastroenteritis-related hospitalization morbidity and mortality among HIV-exposed Indian infants. BMC Infect Dis. 2011 Jul 15; 11(1):193. PMCID:PMC3161884

Staff:

Bob Bollinger, MD, MPH

Amita Gupta, MD, MHS

Nikhil Gupte, PhD

Nishi Suryavanshi, PhD

Collaborators:

Johns Hopkins University-Byramjee Jeejeebhoy Medical College Clinical Trial Unit, Pune, India
Department of Pediatrics, Byramjee Jeejeebhoy Medical College, Pune, India
Department of Clinical Research & Development, Byramjee Jeejeebhoy Medical College, Pune, India
University of Virginia, Center for Public Health Genomic, West Campus, Charlottesville, VA
ICMR/National Aids Research Institute, Pune, India
Maharashtra Universities of Health Sciences, Nasik, India
Division of Infectious Diseases, Weill Cornell Medical College, New York City, NY