Dr. Chhaya Valvi: Pediatrics

Pune, India
Role: 
Scholar
BJGMC-JHU Fogarty HIV-TB Program Trainee

Education:
MBBS (1997) ; DCH (1999) ; MD -Pediatrics (2000).
Medical Education - Seth G.S. Medical College and  K.E.M. Hospital, Mumbai.  Mumbai  University, India.

Overview:
Dr. Chhaya Valvi has completed her undergraduate and postgraduate medical education from the premier institute of Seth G.S. Medical College, Mumbai, India. She was awarded the prestigious Dr. Palekar prize as she ranked first among the candidates for M.D. exam.

Dr. Chhaya is presently working as an Assistant Professor in the Department of Pediatrics, Byramjee Jeejeebhoy Government Medical College (B.J.G.M.C.) and Sassoon General Hospital (SGH), Pune, India. She is In charge of the Neonatal Intensive Care Unit (NICU), High Dependency Unit (HDU) and Deputy In charge of the Human Milk Bank (HMB). She has 16 publications in National and International Journals.

Dr. Chhaya believes for successful treatment outcome in tuberculosis the co-morbid conditions need to be addressed with dedication. As part of the BJGMC JHU Fogarty training program in HIV-TB she is interested in researching on the complex relationship between tuberculosis and malnutrition.  Research with the endpoint of successful nutritional intervention for prevention of TB, which is one of the key tools, can be formulated where both Tuberculosis and Malnutrition are like double edged sword in developing countries. Nutritional intervention based approach may help in improving the treatment outcome, adherence, relapse, mortality and emergence of MDR TB. Further whether macro and micronutrient intervention may prevent progression of Latent Tuberculosis to active TB is the topic she would like to research further with the availability of backup facility of Nutritional Rehabilitation Center and the dedicated Pediatric TB OPD facility available at SGH. Dr. Chhaya is part of a team who has developed an innovative tool “Barrier device for air borne diseases – mainly tuberculosis” (Provisional Patent registered.)

Faculty Mentor(s): 
Bob Bollinger, MD, MPH
Amita Gupta, MD, MHS

Prevalence of Tuberculosis in Severely Malnourished Indian Children

Post Date: 
2018-12-18
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
This study is funded and conducted under the U.S. National Institutes of Health, Fogarty International Center. PIs are Robert Bollinger, MD, MPH; Dr. Muralidhar Tambe, BJGMC Severely malnourished children are vulnerable population for communicable and non-communicable...

Optimal Approach for TB Screening among HIV Infected Indian Children

Post Date: 
2018-06-11
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
This study was terminated May 20, 2019. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. Determining TB status (ie, uninfected, latent, and active TB disease) is more difficult among children, particularly HIV-infected children...

Optimizing Treatment to Improve TBM Outcomes in Children: Substudy on Clinical Profile and CSF Biorepository of the Pediatric Suspected Meningitis Cases

Post Date: 
2017-07-18
   |   
Countries: 
India
Malawi
   |   
Clinical Sites: 
BJGMC
NIRT
This sub-study is being led by PIs Dr. Kelly Dooley and Dr. Chhaya Valvi. Meningoencephalitis is associated with significant morbidity and mortality. Several viruses, bacteria, and fungal pathogens including Neisseria meningitidis, Streptococcus pneumoniae, Mycobacterium...

Risk Factors for Unfavourable Treatment Outcomes among Multidrug-Resistant Tuberculosis Patients in Public Sector Treatment in Pune

Post Date: 
2017-03-29
   |   
Countries: 
India
This study is funded and conducted under the U.S. National Institutes of Health, Fogarty International Center. This study seeks to identify risk factors associated with unfavourable treatment outcomes (death, treatment failure, default, XDR-TB) among multidrug-resistant...

Mullen Scales of Early Learning Adaptation for Assessment of Indian Children and Application to Tuberculous Meningitis

Post Date: 
2020-07-04
   |   
Countries: 
India
Publication: 
Journal of Tropical Pediatrics
Introduction: Tuberculous meningitis (TBM) results in significant morbidity and mortality among children worldwide. Associated neurocognitive complications are common but not well characterized. The Mullen Scales of Early Learning (MSEL), a well-established measure for assessment of...

Transcriptomic profiles of confirmed pediatric tuberculosis patients and household contacts identifies active tuberculosis, infection, and treatment response among Indian children

Post Date: 
2019-12-04
   |   
Clinical Sites: 
BJGMC
NIRT
Publication: 
Journal of Infectious Diseases
Journal of Infectious Diseases: Gene expression profiles among Indian children with confirmed TB were distinct from those of adults, highlighting the importance of including distinct populations in differential gene expression models

Challenges in conducting trials for pediatric tuberculosis meningitis: lessons learned in the field

Post Date: 
2019-10-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
NIRT
Publication: 
International Journal of Tuberculosis and Lung Disease
International Journal of Tuberculosis and Lung Disease: Researchers describe the challenges associated with conducting the first randomized clinical trial of antimicrobial agents in pediatric tuberculosis meningitis.

Delays and barriers to early treatment initiation for childhood tuberculosis in India

Post Date: 
2019-10-01
Publication: 
International Journal of Tuberculosis and Lung Disease
BACKGROUND: India accounts for 27% of global childhood tuberculosis (TB) burden. Understanding barriers to early diagnosis and treatment in children may improve care and outcomes. METHODS: A cross-sectional study was performed among 89 children initiated on anti-TB treatment from a public hospital...

Drug-resistant Enterobacteriaceae colonization is associated with healthcare utilization and antimicrobial use among inpatients in Pune, India

Post Date: 
2018-10-04
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
BMC Infectious Diseases
BACKGROUND: Healthcare exposure may increase drug-resistant Enterobacteriaceae colonization risk. Nascent antimicrobial stewardship efforts in low- and middle-income countries require setting-specific data. We aimed to evaluate risk factors for inpatient drug resistant...

Barriers to screening and isoniazid preventive therapy for child contacts of tuberculosis patients

Post Date: 
2018-10-01
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
International Journal of Tuberculosis and Lung Disease
Universal, timely TB screening and IPT for exposed children are urgently needed to reduce pediatric TB in India

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting

Post Date: 
2018-08-01
   |   
Countries: 
India
Publication: 
PLoS One
World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

Post Date: 
2018-06-25
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
HIV Medicine
Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India

Post Date: 
2018-05-02
   |   
Countries: 
India
   |   
Clinical Sites: 
BJGMC
Publication: 
Clinical Infectious Diseases
Mosquito-borne disease identification is associated with reduced empiric antibiotic use and faster antibiotic discontinuation.

Vector-borne disease is a common cause of hospitalized febrile illness in India

Post Date: 
2018-03-26
   |   
Clinical Sites: 
BJGMC
Publication: 
American Journal of Tropical Medicine and Hygiene
Diagnostic strategies adapted for season and age may reduce diagnostic uncertainty and identify causative organisms in treatable, fatal causes of AFI.

Mexico conference: Experts from BJ Medical College make presentations on TB, treatment

Post Date: 
2017-11-09
Source: 
The Indian Express
Four fellows from the BJGMC-JHU Fogarty HIV-TB Training Program make national headlines in India.