Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
Post Date:
2021-01-18
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Publication:
ERJ Open Resource
Summary:
Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. http://openres.ersjournals.com/lookup/doi/10.1183/23120541.00390-2020?ctkey=shareline&utm_medium=shareline&utm_source=00390-2020&utm_campaign=shareline
Citation:
Gupte AN, Selvaraju S, Gaikwad S, Mave V, Kumar P, Babu S, Andrade BB, Checkley W, Bollinger R, Gupta A. Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis. ERJ Open Res. 2021 Jan 18;7(1):00390-2020. doi: 10.1183/23120541.00390-2020. PMID: 33532468; PMCID: PMC7836581.
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