Characterising cause of death among people treated for drug-susceptible TB in India

Post Date:

2023-01-12

Countries:

Publication:

The International Journal of Tuberculosis and Lung Disease

Summary:

Annually, 1.5 million people die of TB.1 India has thehighest burden of TB,1 and in 2020, the case fatality ratio (CFR) among people with drug-susceptible TB was 4.3%.2 Even after treatment, mortality is more
than two-fold higher among people with prior TB compared to the general population.3,4 However, information about cause of death, particularly in India, is limited. Thus, we sought to characterise cause of death among individuals who accessed TBcare.

From 2013 to 2018, we enrolled individuals within 1 week of being diagnosed with drug-susceptible TB at public clinics in Pune and Chennai, India, into two pooled prospective cohorts.5,6 Participants received care according to India’s standard guidelines and were followed up to 18 months post-treatment. Sociodemographic and clinical data were collected at enrolment and microbiological results were tracked. Considering low paediatric mortality, participants,18 years were excluded.

Citation:

Cox, S. R.; Padmapriyadarsini, C.; Mave, V.; Seth, B.; Thiruvengadam, K. ; Gaikwad, S.; Sahasrabudhe, T. R.; Sane, M.; Tornheim, J. A.; Shrinivasa, B. M.; Lokhande, R.; Barthwal, M. S.; Shivakumar, S. V. B. Y.; Krishnan, S.; Santhappan, R.; Kinikar, A.; Kakrani, A. L.; Paradkar, M.; Bollinger, R. C.; Sekar, K.; Gupte, A. N.; Hanna, L. E.; Gupta, A.; Golub, J. E. Int J Tuberc Lung Dis 27(1):78–80 http://dx.doi.org/10.5588/ijtld.22.0454

Staff:

Bob Bollinger, MD, MPH

Jonathan Golub, MPH, PhD

Amita Gupta, MD, MHS

Akshay Gupte, PhD, MBBS, MSPH, PhD

Aarti Avinash Kinikar, MD: Pediatrics

Rahul Lokhande, MD: Pulmonary Medicine

Vidya Mave, MD, MPH

Mandar Paradkar, MBBS, DCH, MPH

Shri Vijay Bala Yogendra Shivakumar, MD

Jeff Tornheim, MD, MPH

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