Publications

Neutralizing antibody responses in recent seroconverters with HIV-1 subtype C infections in India

Post Date: 
2008-10-25
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AIDS Research and Human Retroviruses
The longitudinal heterologous neutralization response against two HIV-1 subtype C isolates was studied in 33 ART-naive individuals recently infected with HIV-1 subtype C from India. Seven of 33 (21%) seroconverters demonstrated a consistent response against both isolates (65-100%...

High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune, India

Post Date: 
2008-10-21
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BMC Infectious Diseases
Background: The risk for occupational exposure to HIV has been well characterized in the developed world, but limited information is available about this transmission risk in resource-constrained settings facing the largest burden of HIV infection. In addition, the feasibility and utilization of...

Repeated pregnancy in HIV positive Indian women with known HIV status

Post Date: 
2008-09-29
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AIDS Care
HIV-positive women of reproductive age face challenges in decision making related to pregnancy. Understanding factors influencing repeat pregnancies in women with known HIV status are necessary to guide interventions and counseling strategies to better inform and support them. We compared...

The Indian pediatric HIV epidemic: a systematic review

Post Date: 
2008-09-15
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Current HIV Research
Despite an estimated 70,000 Indian children living with HIV infection, little is known about India's pediatric HIV epidemic. Generalizations about epidemiology, natural history, and treatment outcomes from other resource-limited settings (RLS) may be inaccurate for several biologic and social...

Incidence of common opportunistic infections in HIV-infected individuals in Pune, India: analysis by stages of immunosuppression represented by CD4 counts

Post Date: 
2008-07-02
Publication: 
International Journal of Infectious Diseases
Background: Opportunistic infections (OIs) influence the morbidity and mortality due to HIV infections. Data from India on the incidence of OIs among HIV-infected individuals by stages of immunodeficiency are scarce. Methods: Between September 2002 and...

Low utilization of HIV testing during pregnancy: what are the barriers to HIV testing for women in rural India?

Post Date: 
2008-02-01
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Journal of Acquired Immune Deficiency Syndromes
Introduction: Sixty percent of India's HIV cases occur in rural residents. Despite government policy to expand antenatal HIV screening and prevention of maternal-to-child transmission (PMTCT), little is known about HIV testing among rural women during pregnancy. ...

Modeling maternal infant HIV transmission in the presence of breast-feeding with an imperfect test

Post Date: 
2007-12-15
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Biometrics
An important public health question is to determine the probabilities of perinatal HIV transmission and when it occurs, whether antepartum, intrapartum, or postpartum through breastfeeding. However, this is a difficult problem because the presence of HIV infection in an infant can only be...

Selenium and HIV-1: Hope or hype?

Post Date: 
2007-12-10
Publication: 
Archives of Internal Medicine
We read with great interest the article by Hurwitz et al on the impact of selenium supplementation in patients infected with human immunodeficiency virus type 1 (HIV-1). Studies examining the association between micronutrients and HIV, particularly prospective studies, have been limited to...

Are we really making motherhood safe? A study of provision of iron supplements and emergency obstetric care in rural Maharashtra

Post Date: 
2007-11-30
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National Medical Journal of India
Abstract Background: The Government of India launched the National Rural Health Mission (NRHM) in 2005 to improve healthcare delivery and strengthen the public health system. Prevention and management of anaemia during pregnancy and access to quality emergency obstetric care...

Nurses’ health education program in India increases HIV knowledge and reduces fear

Post Date: 
2007-11-30
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Journal of the Association of Nurses in AIDS Care
Few health care facilities are adequately prepared to manage and care for HIV/AIDS patients in India. Nurses play a critical role in patient care but are often ill-equipped to deal with their own fears of occupational risk and handle the clinical aspects of HIV/AIDS care, leading to stigma and...

Low sensitivity of total lymphocyte count as a surrogate marker to identify antepartum and postpartum Indian women who require antiretroviral therapy

Post Date: 
2007-11-01
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Journal of Acquired Immune Deficiency Syndromes
Background: Some studies support the use of total lymphocyte count (TLC) as a surrogate marker for CD4 cell count to guide antiretroviral therapy (ART) initiation. However, most of these studies have focused on nonpregnant adults. In light of expanding ART access through prevention of mother-...

Declining HIV infection rates among recently married, pregnant women in Pune, India

Post Date: 
2007-08-15
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Journal of Acquired Immune Deficiency Syndromes
Background: A single recent study has suggested a decrease in HIV risk for women attending antenatal clinics (ANCs) in southern India. Yet, some have questioned the validity of the Indian national surveillance data and analyses. Previous studies suggest that the only major HIV risk factor for...

Mother-to-child transmission of HIV among women who chose not to exclusively breastfeed their infants in Pune, India

Post Date: 
2007-08-15
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Indian Journal of Medical Research
Background and Objective: The percentage of HIV cases attributed to mother-to-child transmission (MTCT) has increased several fold in recent years. No reports are available on HIV MTCT rates among HIV-infected choosing not be exclusively breastfeed their infants in India. We examined HIV MTCT...

Declining HIV Incidence among patients attending sexually transmitted infection clinics in Pune, India

Post Date: 
2007-08-15
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Journal of Acquired Immune Deficiency Syndromes
Objective: A recent report suggesting declining HIV transmission rates in southern India has been based on HIV seroprevalence data to estimate HIV incidence. We analyzed HIV incidence rates among 3 cohorts (male, female non-sex worker, female sex worker [FSW]) presenting to sexually...

Mortality and clinical characteristics of hospitalized adult patients with HIV in Pune, India

Post Date: 
2007-08-01
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Indian Journal of Medical Research
Background and Objective: In India, data regarding mortality and clinical characteristics of hospitalized HIV-infected patients are sparse, which may limit the effectiveness of new hospital-based HIV programmes providing antiretroviral therapy (ART). The objective of our study was to...

Post-partum TB incidence and mortality among HIV-infected women and their infants in Pune, India 2002-2005

Post Date: 
2007-07-15
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Clinical Infectious Diseases
Background: In contrast with many other countries, isoniazid preventative therapy is not recommended in clinical care guidelines for human immunodeficiency virus (HIV)-infected persons with latent tuberculosis (TB) in India. Methods: Seven hundred fifteen...

Hematogenous osteomyelitis mimicking osteosarcoma due to Community Associated Methicillin-Resistant Staphylococcus aureus

Post Date: 
2007-06-15
Publication: 
Infection
Community Associated Methicillin - Resistant Staphylococcus aureus (CA-MRSA) is an emerging pathogen with increasing clinical significance. Initially recognized as a cause of skin and soft tissue infections, it has soon been shown to cause life threatening illnesses. We describe two cases of...

Clinically significant anemia in HIV-infected pregnant women in India is not a major barrier to zidovudine use for prevention of maternal-to-child transmission

Post Date: 
2007-06-01
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Journal of Acquired Immune Deficiency Syndromes
Objectives: To determine the prevalence of anemia (serum hemoglobin <10 g/dL) and assess zidovudine use and toxicity in HIV-positive pregnant women in India. Methods: From 2002 through 2006, 24,105 pregnant women in Pune were screened for HIV and anemia. As part of...

Adherence to antiretroviral therapy and virologic suppression among HIV-infected persons receiving care in private clinics in Mumbai, India

Post Date: 
2007-05-01
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Clinical Infectious Diseases
Background: Adherence to antiretroviral therapy (ART) and correlates of adherence and virologic suppression among human immunodeficiency virus (HIV)-infected persons receiving ART in private, outpatient clinics in India is unknown. Methods: Between December...

Impact of maternal HIV co-infection on the vertical transmission of Hepatitis C virus: a meta-analysis.

Post Date: 
2007-04-15
Publication: 
Clinical Infectious Diseases
Background: Observational studies suggest that maternal human immunodeficiency virus (HIV)-hepatitis C virus (HCV) coinfection is associated with increased odds of vertical HCV transmission. We performed a meta-analysis to summarize current evidence. Methods...

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